Results 261 to 270 of about 21,862 (343)

Modification of aspartate aminotransferase with heavy atoms and with coenzyme analogs

, 1980
Jane Ann Schmidt
openalex   +1 more source

Cationic Nanoparticles Mitigate Chemotherapy‐Induced Peripheral Neuropathy

Advanced NanoBiomed Research, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN), caused by chemodrugs like paclitaxel (PTX), leads to severe neuropathic pain. This study evaluates PTX‐loaded PAMAM‐Chol nanoparticles (PTX‐NPs) to alleviate CIPN. PTX‐NPs achieve 99% drug‐loading efficiency, reduce neurotoxicity, and in murine models, decrease cold allodynia by 85% while restoring ...
Divya Bhansali, Rocco Latorre, Raquel Tonello, David Poolman, Suwan Ding, Brian L. Schmidt, Nigel W. Bunnett, Kam W. Leong   +7 more
wiley   +1 more source

Hepatic Inflammation Primes Vascular Dysfunction Following Treatment with LPS in a Murine Model of Pediatric Fatty Liver Disease. [PDF]

Int J Mol Sci
Huang H, Shoemaker R, Alsiraj Y, Murphy M, Gibbons TE, Bauer JA.   +5 more
europepmc   +1 more source

Refining Liver Safety Risk Assessment:Application of Mechanistic Modeling and Serum Biomarkers to Cimaglermin Alfa (GGF2) Clinical Trials [PDF]

, 2017
Antoine, Antoine, Boyd, Clarke, Davidson, Harrill, Howell, Kramer, Longo, Mosedale, Murayama, Nicoll, Poelzl, Portmann, Prescott, Rej, Remien, Samsky, Schiødt, Schmidt, Shoda, Singer, Smit, Sohlenius-Sternbeck, Starkey Lewis, Stutchfield, Temple, Thulin, Vyskocilova, Watkins, Woodhead, Yang   +31 more
core   +1 more source

lnfluences of Some Low Molecular Compounds on Enzymatic Activity and Isolectric Point of Aspartate Aminotransferase from Rat Liver.

, 1993
Mitsuko OKADA, Hitomi HARIMA, Yoko Hosoi, Akiko Sogo   +3 more
openalex   +2 more sources

Tuning Cellular Perception in Pluripotent Stem Cells through Topography, Stiffness, and Patterning

Advanced NanoBiomed Research, EarlyView.
Micro‐ and nanotopographical cues, substrate stiffness, and mechanical patterning synergistically direct pluripotent stem cell fate and function by tuning cellular perception at the biointerface. Pluripotent stem cells (PSCs), comprised of embryonic stem cells and induced PSCs, hold tremendous therapeutic potential.
Yuan Jiang, Jann Harberts, Yaping Chen, Richard J. Williams, Wei Duan, Rasika M. Samarasinghe, Nicolas H. Voelcker, Roey Elnathan   +7 more
wiley   +1 more source

Effects of 12-weeks resistance training and vitamin E supplementation on aminotransferases, CTRP-2, and CTRP-9 levels in males with nonalcoholic fatty liver disease: a double-blind, randomized trial. [PDF]

BMC Sports Sci Med Rehabil
Varmazyar I, Monazzami AA, Moradi M, McAinch AJ.   +3 more
europepmc   +1 more source

Dependence of the folding and import of the precursor to mitochondrial aspartate aminotransferase on the nature of the cell-free translation system.

, 1994
Blanca Lain, Ana Iriarte, Marino Martinez‐Carrion   +2 more
openalex   +1 more source

Oral Delivery of Chitosan‐Rosmarinic Acid Nanoparticles Ameliorates Mucosal Inflammation in a Mouse Model of Colitis

Advanced NanoBiomed Research, EarlyView.
Orally administered low molecular weight chitosan–rosmarinic acid nanoparticles demonstrate potent anti‐inflammatory effects in a mouse model of colitis by scavenging reactive oxygen species, preserving intestinal barrier integrity, and modulating immune responses, underscoring their promise as an effective nanomedicine for inflammatory bowel disease ...
Afia Tasnim Rahman, Sungyeon Kang, Sangyong Jon   +2 more
wiley   +1 more source

A Case Report of a 61-Year-Old Woman With Jaundice and Cholelithiasis Presenting With Autoimmune Hepatitis. [PDF]

Cureus
Michalakis NP, Patel A, Awais M.
europepmc   +1 more source