Results 271 to 280 of about 16,662 (295)

A case of aspartate aminotransferase macroenzyme

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2008
Aspartate aminotransferase (AST) macroenzyme can result in elevated AST activity in patients with no disease. This case report describes a six-year-old boy who presented to his family doctor with a history of chronic constipation and lower back pain.
J, Cabrera-Abreu, R, Jain, P, Robinson, S, Edees, T, Staughton   +4 more
openaire   +2 more sources

[Aspartate aminotransferase].

Nihon rinsho. Japanese journal of clinical medicine, 1995
The characteristics and clinical usefulness for aspartate aminotransferase (AST) isoenzyme including apo- and holo-type enzymes were reviewed. The activation effect on mitochondrial- and cytosolic-AST (mAST and cAST) was compared in the presence of PALP, to sera of various diseases such non-alcoholic liver-, heart-, renal, and alcoholic liver diseases.
openaire   +1 more source

Domain closure in mitochondrial aspartate aminotransferase

Journal of Molecular Biology, 1992
The subunits of the dimeric enzyme aspartate aminotransferase have two domains: one large and one small. The active site lies in a cavity that is close to both the subunit interface and the interface between the two domains. On binding the substrate the domains close together.
C A, McPhalen, M G, Vincent, D, Picot, J N, Jansonius, A M, Lesk, C, Chothia   +5 more
openaire   +2 more sources

Strain and catalysis in aspartate aminotransferase

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2003
The notion of "ground-state destabilization" has been well documented in enzymology. It is the unfavourable interaction (strain) in the enzyme-substrate complex, and increases the k(cat) value without changing the k(cat)/K(m) value. During the course of the investigation on the reaction mechanism of aspartate aminotransferase (AAT), we found another ...
Hideyuki, Hayashi, Hiroyuki, Mizuguchi, Ikuko, Miyahara, Mohammad Mainul, Islam, Hiroko, Ikushiro, Yoshitaka, Nakajima, Ken, Hirotsu, Hiroyuki, Kagamiyama   +7 more
openaire   +2 more sources

Aminotransferases in Grapes. Isolation and Characterization of Aspartate Aminotransferase

American Journal of Enology and Viticulture, 1991
International ...
Sauvage, F.X., Romieu, C.G., Flanzy, C., Robin, J.P.   +3 more
openaire   +2 more sources

Immobilization of aspartate aminotransferase on agarose

Biochimie, 1989
Various methods for immobilization of aspartate aminotransferase (AspAT; from cytosolic fraction of pig heart) on agarose were tested. Aldehyde-, thiol-, and CNBr-activated agaroses were studied in detail. The capacity of the aldehyde support to firmly bind protein was less than 0.2 mg/ml, whereas the apparent remaining specific activity of the bound ...
K, Kurkijärvi, T, Korpela
openaire   +2 more sources

Is Aspartate Aminotransferase Enough?

American Journal of Gastroenterology, 2000
GIANNINI, EDOARDO GIOVANNI, TESTA, ROBERTO   +1 more
openaire   +3 more sources

Cytosolic aspartate aminotransferase

Biochimica et Biophysica Acta (BBA) - Protein Structure, 1978
Hansjörg Schlegel, Philipp Christen
openaire   +1 more source

Aspartate aminotransferase.

2015
C. D. Leasure, Z. H. He
openaire   +1 more source

Primary structures of aspartate aminotransferases

Biochemical Society Transactions, 1984
F, Bossa, D, Barra, S, Doonan
openaire   +2 more sources