Results 151 to 160 of about 106,281 (309)

Responses of plasma transaminase activity in Cyprinus carpio var. communis to mercury toxicity [PDF]

, 2002
The present study reports the behavioural and enzymological responses in a freshwater teleost fish, Cyprinus carpio var. communis, exposed to acute and sublethal toxicities of mercuric chloride.
Ramanujam, M., Ramesh, M., Sampath, H.
core  

Persistent Elevation of Aspartate Amino Transferase: Macroenzymes: Case Report

Turkiye Klinikleri Journal of Case Reports, 2016
Funda UĞUR KANTAR, Aydan ÇELEBİLER
openaire   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

The Dynamic Evolution of Lipid Profiles Following Transjugular Intrahepatic Portosystemic Shunt in Patients With Liver Cirrhosis

Portal Hypertension &Cirrhosis, EarlyView.
Cirrhosis is frequently accompanied by varying degrees of lipid profile abnormalities. This study confirms that these profiles are differentially affected by disease etiology and progressively worsen—with significant reductions in TC, HDL‐C, and LDL‐C—as liver disease severity increases. TIPS improves lipid profiles, particularly by increasing HDL‐C in
Jiamin Xu, Qinnian Li, Lagan Kumar Manandhar, Bilian Zhu, Chenrui Zhang, Weimin Bao, Yingmei Tang   +6 more
wiley   +1 more source

Synthesis and intracellular transport of mitochondrial proteins [PDF]

, 1985
A Lustig, A Lustig, A Ohashi, A Viebrock, AJ Lamb, AP Autor, AS Lewin, AS Lewin, B Hennig, B Schmidt, BE Roberts, BG Barrell, C Cote, C Zwizinski, CJ Leaver, DI Meyer, DI Meyer, DL Stigall, DM Kolansky, E Komar, E Marra, E Pratje, E Schmelzer, G Attardi, G Blobel, G Daum, G Daum, G Hallermayer, G Hallermayer, G Kreibich, G Kreil, G Macino, G Reid, G Schatz, G Schatz, G Schatz, G Srivastava, GC Shore, GC Shore, H Freitag, H Koehler, H Korb, H Riezman, H Weiss, IG Macreadie, IZ Ades, IZ Ades, J Kaput, JG Conboy, JP Kraus, K Mihara, K Mihara, K Mihara, K Watanabe, L Ernster, L Randall, LA Grivell, LE Aziz, M Inouye, M Klingenberg, M Klingenberg, M Maccechini, M Mori, M Mori, M Schleyer, M Suissa, M Teintze, M Wikstrom, M Yamamoto, M-L Maccechini, MA Harmey, MA Harmey, MD Hampsey, MM Mueckler, N Cerletti, N Nabi, N Nelson, NK Bhat, P Boehni, P Boehni, P Boogart van den, P Borst, P Borst, P Borst, P McAda, P Sonderegger, P Walter, PC Heinrich, PC Kreibich, PG Adolphus, R Jaussi, R Michel, R Sakakibara, R Zimmermann, R Zimmermann, R Zimmermann, R Zimmermann, RE Kellems, RE Kellems, RO Poyton, S Matsuura, S Miura, S Passarella, S Werner, SD Emr, SM Gasser, SM Gasser, SM Gasser, T Hunt, T Monta, T Oda, VA Rucker, W Neupert, W Wickner, Y Kamisaki, Y Raymond, Y Sagara, Y Yoshida   +117 more
core   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source

Comparable Diagnostic Accuracy but Discordant Thresholds Between FibroTouch and FibroScan: A Biopsy‐Based Comparative Study

Portal Hypertension &Cirrhosis, EarlyView.
In this biopsy‐controlled study, FibroTouch and FibroScan demonstrated comparable diagnostic accuracy for liver fibrosis staging (AUROCs > 0.900), but FibroTouch required consistently higher stiffness thresholds. These discrepancies were more pronounced in patients with MAFLD, highlighting the need for device‐specific cutoffs to avoid misclassification.
Min Wang, You Deng, Guanhua Zhang, Xinyan Zhao, Xiaoming Wang, Xiaojuan Ou, Min Li, Hong Ma, Yu Wang   +8 more
wiley   +1 more source

Integrated genomic and transcriptomic approaches reveal oxidative stress adaptation mechanisms in a mesotrione‐resistant Amaranthus tuberculatus biotype

Pest Management Science, EarlyView.
Integrated GWAS and transcriptomics in a Canadian waterhemp biotype reveal mesotrione resistance is polygenic and metabolically driven. Significant SNPs and 187 herbicide‐responsive genes point to enhanced redox homeostasis, glutathione‐linked detoxification, lipid/secondary metabolism, and oxidative stress responses. Resistance arises from coordinated,
Martin Laforest, Marianne Bessette, Geneviève Gagnon, Sandra Flores‐Mejia, Brahim Soufiane, Marie‐Claire Goulet, Dominique Michaud   +6 more
wiley   +1 more source

Pedunculoside Inhibits Hepatocellular Carcinoma Progression by Activating the MAPK Signaling Pathway Through Targeting and Suppressing CDK4

Phytotherapy Research, EarlyView.
Pedunculoside targets and suppresses CDK4; consequently, it activates the MAPK pathway and inhibits hepatocellular carcinoma progression. ABSTRACT Hepatocellular carcinoma (HCC) remains a major challenge in cancer prevention and treatment, highlighting the urgent need for effective and low‐toxicity anti‐HCC therapies. Recently, CDK4‐targeted inhibitors
Yang Zhou, Jingyun Chi, Yuan Ding, Zhidi Zhang, Rui Liang, Tianhao Wang, Yan Jiang, Rujun Song, Huazhou Fu, Xizhen Zhou   +9 more
wiley   +1 more source

Exploring the Impact of Polystyrene Microplastic Beads on Male Gonads of the Marine Mussel, Mytilus galloprovincialis

Environmental Toxicology, EarlyView.
ABSTRACT Plastic, with its remarkable versatility and numerous applications, has greatly benefited humanity. However, its extreme resistance to natural degradation means it persists in the environment for long periods, causing global environmental problems.
Teresa Chianese, Mariachiara Galati, Tiziana Cappello, Maria Maisano, Gennaro Lettieri, Carmela Marinaro, Marina Piscopo, Gianluca Fasciolo, Carlos Gravato, Gaetana Napolitano, Giulia Paolella, Annamaria Locascio, Rosaria Scudiero, Luigi Rosati   +13 more
wiley   +1 more source