Results 231 to 240 of about 106,281 (309)

Maternal Dyslipidaemia Aggravates Offspring Metabolic Dysfunction–Associated Steatotic Liver Disease

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 138, Issue 6, June 2026.
ABSTRACT Paediatric metabolic dysfunction–associated steatotic liver disease (MASLD) and steatohepatitis (MASH) display a distinct and severe histopathology. Maternal metabolic status may program offspring susceptibility to MASLD. This study investigated if maternal dyslipidaemia and low vitamin C (VitC) status influence offspring MASLD using a ...
Kamilla Pedersen   +4 more
wiley   +1 more source

Proteomic Profiling of Plasma to Uncover Novel Intervention Targets and Prognostic Biomarkers for Chronic Liver Diseases

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 5029-5042, June 2026.
ABSTRACT Aims The burden of chronic liver disease (CLD) is increasing. This study aims to identify protein markers for CLD and its progression, and develop a protein‐based risk prediction model. Materials and Methods We used proteome‐wide Mendelian randomization (MR), Bayesian colocalization and summary‐data‐based MR with proteomic data from deCODE ...
Xinxuan Li   +9 more
wiley   +1 more source

Risk Stratification of Chronic Kidney Disease in Adults Using Noninvasive Fibrosis Tests Based on the American Diabetes Association Algorithm

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 5240-5251, June 2026.
ABSTRACT Aims Although the American Diabetes Association (ADA) recently established a diagnostic algorithm for the early detection of liver fibrosis among high‐risk individuals, its implications for chronic kidney disease (CKD) risk stratification remain unclear.
Chan‐Young Jung   +4 more
wiley   +1 more source

Induction of Clinical Operational Tolerance Through Immunosuppression Minimization: Less Is More?

open access: yesLiver International, Volume 46, Issue 6, June 2026.
ABSTRACT The goal of achieving clinical operational tolerance in liver transplantation has sparked significant interest, driven by the desire to mitigate the long‐term adverse effects of immunosuppression. Advances in understanding the immunological mechanisms underpinning operational tolerance in liver transplantation have highlighted the central role
Emilia Knioła   +4 more
wiley   +1 more source

Short-Term Outcome of Infants with Biliary Artesia Following Kasai Portoenterostomy. [PDF]

open access: yesIndian J Pediatr
Elhadary NM   +5 more
europepmc   +1 more source

Relative Exchangeable and Exchangeable Copper: Emerging New Biomarkers for Diagnosis and Therapy Monitoring in Wilson's Disease

open access: yesLiver International, Volume 46, Issue 6, June 2026.
ABSTRACT Background and Aims Wilson's disease (WD) is a genetic disorder of copper metabolism in which early diagnosis remains challenging, particularly in acute liver failure (ALF). Relative exchangeable copper (REC) and exchangeable copper (CuEXC) are emerging biomarkers for diagnosis and monitoring, but data from larger cohorts are limited.
Sebastian Köhrer   +10 more
wiley   +1 more source

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