Maternal Dyslipidaemia Aggravates Offspring Metabolic Dysfunction–Associated Steatotic Liver Disease
ABSTRACT Paediatric metabolic dysfunction–associated steatotic liver disease (MASLD) and steatohepatitis (MASH) display a distinct and severe histopathology. Maternal metabolic status may program offspring susceptibility to MASLD. This study investigated if maternal dyslipidaemia and low vitamin C (VitC) status influence offspring MASLD using a ...
Kamilla Pedersen +4 more
wiley +1 more source
Distinct Laboratory and Clinical Features of Metabolic and Alcohol-Related Liver Disease (MetALD): A Systematic Review and Meta-Analysis. [PDF]
Tampaki M +4 more
europepmc +1 more source
ABSTRACT Aims The burden of chronic liver disease (CLD) is increasing. This study aims to identify protein markers for CLD and its progression, and develop a protein‐based risk prediction model. Materials and Methods We used proteome‐wide Mendelian randomization (MR), Bayesian colocalization and summary‐data‐based MR with proteomic data from deCODE ...
Xinxuan Li +9 more
wiley +1 more source
Effects of carotenoid supplementation on liver enzymes in adults: a GRADE-assessed systematic review and dose-response meta-analysis of randomized controlled trials. [PDF]
Heydari SS +4 more
europepmc +1 more source
ABSTRACT Aims Although the American Diabetes Association (ADA) recently established a diagnostic algorithm for the early detection of liver fibrosis among high‐risk individuals, its implications for chronic kidney disease (CKD) risk stratification remain unclear.
Chan‐Young Jung +4 more
wiley +1 more source
Indirect estimation of serum enzymes reference intervals in adults using the reflimR and refineR algorithms. [PDF]
Yıldız R, Arslan FD, Köseoğlu M.
europepmc +1 more source
Induction of Clinical Operational Tolerance Through Immunosuppression Minimization: Less Is More?
ABSTRACT The goal of achieving clinical operational tolerance in liver transplantation has sparked significant interest, driven by the desire to mitigate the long‐term adverse effects of immunosuppression. Advances in understanding the immunological mechanisms underpinning operational tolerance in liver transplantation have highlighted the central role
Emilia Knioła +4 more
wiley +1 more source
Short-Term Outcome of Infants with Biliary Artesia Following Kasai Portoenterostomy. [PDF]
Elhadary NM +5 more
europepmc +1 more source
ABSTRACT Background and Aims Wilson's disease (WD) is a genetic disorder of copper metabolism in which early diagnosis remains challenging, particularly in acute liver failure (ALF). Relative exchangeable copper (REC) and exchangeable copper (CuEXC) are emerging biomarkers for diagnosis and monitoring, but data from larger cohorts are limited.
Sebastian Köhrer +10 more
wiley +1 more source
Establishment and Validation of a Nomogram Based on Inflammation-Immunity-Nutrition Biomarker Scores to Predict Postoperative Early Recurrence in Patients with Hepatocellular Carcinoma: A Multicenter Study. [PDF]
Zhang Y +6 more
europepmc +1 more source

