Results 41 to 50 of about 106,281 (309)

Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study

open access: yesHepatology, EarlyView., 2022
Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel   +93 more
wiley   +1 more source

Structure and Function of a Mycobacterial NHEJ DNA Repair Polymerase [PDF]

open access: yes, 2006
Non homologous end-joining (NHEJ)-mediated repair of DNA double-strand breaks in prokaryotes requires Ku and a specific multidomain DNA ligase (LigD).
Aidan J. Doherty   +59 more
core   +1 more source

U Mass - Aspartate Transferase v1 [PDF]

open access: yes, 2019
Summary: This experiment involves a spectrophotometric measurement using Roche Cobas Clinical Chemistry Analyzer. Serum levels of aspartate transferase reflect liver function.
openaire   +1 more source

Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double‐blind, placebo‐controlled clinical trial

open access: yesHepatology, EarlyView., 2022
NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger   +7 more
wiley   +1 more source

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

open access: yesHepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli   +13 more
wiley   +1 more source

Effect of aqueous extract of Capparis spinosa on biochemical and histological changes in paracetamol–induced liver damage in rats [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2012
This study showed that paracetamol administration to male rats at 1 g /kg of body weight for 21 days resulted in significant increase in activities of serum alanine amino transferase and aspartate amino transferase.
R. J. M. Alnuaimy, H. I. A. Al-khan
doaj  

Comparison of Machine Learning Classification Methods in Hepatitis C Virus

open access: yesJOIN: Jurnal Online Informatika, 2021
The hepatitis C virus (HCV) is considered a problem to the health of societies are the main. There are around 120-130 million or 3% of the world's total population infected with HCV.
Lailis Syafa’ah   +3 more
doaj   +1 more source

Some Biochemical, Haematological and Histological Responses to a Long Term Consumption of Telfairia occidentalis-Supplemented Diet in Rats [PDF]

open access: yes, 2009
Some biochemical, haematological and histological responses were studied in rats undergoing a long term feeding with a Telfairia occidentalis-supplemented diet.
Iweala, E. E. J., Obidoa, O.
core   +1 more source

Hepatoprotactive activity of Ruta chalepensis ethanolic extract and histo-architecture of liver on CCL4 damaged albino male mice

open access: yesمجلة مركز بحوث التقنيات الاحيائية, 2021
       Medicines derivative from  plants  broadly famous owing to  their  safety, obtainability  and  little Leaves, roots,  bark, kernels  and  florae of  plant  are mostly prepared that included herbal medicines.  They are administered orally, inhaled
Hadeel Mohamed khalaf
doaj   +1 more source

Metabolic abnormalities associated with initiation of systemic treatment for psoriasis: evidence from the Italian Psocare Registry. [PDF]

open access: yes, 2013
Objective To evaluate variations in laboratory parameters and diagnoses of selected clinical conditions up to16 weeks after starting a new systemic psoriasis treatment for Psocare Registry enrollees.Design Prospective cohort study.Setting Italian public ...
A., Giannetti   +10 more
core   +1 more source

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