Results 111 to 120 of about 6,287,498 (310)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Auxiliary focus

open access: yesStudies in African Linguistics, 1984
This paper examines the different properties of what we have termed "auxiliary focus": the interaction between focus and the semantic features of tense. aspect, mood. and polarity.
Larry M. Hyman, John R. Watters
doaj  

RECULTIVATED SOIL HETEROGENEITY: ECOLOGICAL ASPECT [PDF]

open access: yes, 2018
Extracting minerals by the open method leads to the removal of the rocks to the surface which significantly disturbs natural processes in biogeocoenoses. After remediation activities anthropogenic biogeocoenoses are formed. In
Andrusevych, Kateryna   +1 more
core  

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

The role of tense and aspect in Mbodomo narrative discourse

open access: yesStudies in African Linguistics, 2000
In Mbodomo, a Gbaya language spoken in Cameroon, the tense/aspect of the verb plays an important role in narrative discourse. In general, tense/aspect is not marked on main clause verbs except in the story setting.
Ginger Boyd
doaj  

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Tone in Abidji morphology

open access: yesStudies in African Linguistics, 1990
This article is a description of the morphology of the regular verbs in Abidji. It shows how segmental and tonal rules interact to produce the realization of 14 tense-aspect combinations in 2 different classes of verbs.
Chantal Tresbarats
doaj  

Femininity Aspect as Reflected in Lisa See\u27s Snow Flower and the Secret Fan [PDF]

open access: yes, 2018
The purpose of this study is to describe forms opression faced by Chinese women in the nineteenth century as reflected in te novel “Snow Flower and the Secret Fan” written by Lisa See, then to find out the way of the Chinese women to minimize their ...
Rakhmyta, Y. A. (Yunie)
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Developing Temporal Systems

open access: yesPsychology of Language and Communication, 2014
This paper reviews a body of research that reveals how children acquire the capacity to express the temporal location of episodes that they remember and those they anticipate for the future. The paper shows how the child’s knowledge of language structure
Weist Richard M.
doaj   +1 more source

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