Results 111 to 120 of about 5,741,184 (344)

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

open access: yesFEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui   +15 more
wiley   +1 more source

Domain adaptive English aspect word extraction method based on bidirectional long and short-term memory network and multi-head attention mechanism

open access: yesJournal of Applied Science and Engineering
English aspect word extraction is a core task of aspect level sentiment analysis. With the continuous development of social networks, more users tend to make decisions based on comment text, and pay more attention to the details of comment text ...
Tianxiao Wang
doaj   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

A Hybrid Frequency Based, Syntax, and Conditional Random Field Method for Implicit and Explicit Aspect Extraction

open access: yesIEEE Access
Aspect extraction is the most important factor influencing the quality of Aspect-Based Sentiment Analysis (ABSA). Aspect extractions are divided into three approaches: supervised, unsupervised, and hybrid methods.
Mohammad Mashrekul Kabir   +2 more
doaj   +1 more source

A high aspect ratio membrane reactor for liquid–liquid extraction [PDF]

open access: green, 2013
Jonas Hereijgers   +7 more
openalex   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

open access: yesFEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns   +2 more
wiley   +1 more source

PASTE: A Tagging-Free Decoding Framework Using Pointer Networks for Aspect Sentiment Triplet Extraction [PDF]

open access: hybrid, 2021
Rajdeep Mukherjee   +4 more
openalex   +1 more source

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

open access: yesFEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel   +3 more
wiley   +1 more source

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