Results 121 to 130 of about 814,629 (342)

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

A Survey on Multimodal Aspect-Based Sentiment Analysis

open access: yesIEEE Access
Multimodal Aspect-Based Sentiment Analysis (MABSA), as an emerging task in the field of sentiment analysis, has recently received widespread attention. Its aim is to combine relevant multimodal data to determine the sentiment polarity of a given aspect ...
Hua Zhao   +3 more
doaj   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

A Hybrid Frequency Based, Syntax, and Conditional Random Field Method for Implicit and Explicit Aspect Extraction

open access: yesIEEE Access
Aspect extraction is the most important factor influencing the quality of Aspect-Based Sentiment Analysis (ABSA). Aspect extractions are divided into three approaches: supervised, unsupervised, and hybrid methods.
Mohammad Mashrekul Kabir   +2 more
doaj   +1 more source

Progressive Self-Training with Discriminator for Aspect Term Extraction [PDF]

open access: hybrid, 2021
Qianlong Wang   +4 more
openalex   +1 more source

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