Results 51 to 60 of about 2,039,612 (296)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Dual equilibrium in a finite aspect ratio tokamak [PDF]

open access: yes, 2008
A new approach to high pressure magnetically-confined plasmas is necessary to design efficient fusion devices. This paper presents an equilibrium combining two solutions of the Grad-Shafranov equation, which describes the magnetohydrodynamic equilibrium ...
Aymar   +15 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Biological and Ecological Studies of the Ash Whitefly Siphoninus Phillyreae (HALIDAY) (Hemiptera: Aleyrodidae) on Citrus

open access: yesBioscientific Review, 2019
Siphoninus phillyreae (Ash Whitefly) belongs to class Insecta, family Aleyrodidae, and genus Siphoninus. S. phillyreae is widely distributed in Middle East, Europe, Central and North Africa.
Al-Nadawi Fayhaa Abbood Mahdi
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

A SITE-BASED PRACTICAL IMPROVISATION FOR THE ANALYTICAL DETERMINATION OF ASPECT RATIO

open access: yesArchitecture and Engineering, 2017
'Aspect Ratio', a commonly used indicator to describe typical urban geometry is computed as the average ratio of the building heights ‘H’ to the canyon width 'W'.
Rajesh Gopinath, Deepak D.G
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Some aspects of barreling in sintered plain carbon steel powder metallurgy preforms during cold upsetting

open access: yesMaterials Research, 2012
The present research establishes a relationship of bulged diameter with densification and hydrostatic stress in forming of sintered iron (Fe) powder metallurgy preforms cold upset under two different frictional conditions, namely, nil/no and graphite ...
Sumesh Narayan   +1 more
doaj  

Study of Shear Stress Distribution in a Compound Rectangular Section [PDF]

open access: yesعلوم و مهندسی آبیاری, 2013
Reliable prediction of boundary shear force distributions in open channel flow is crucial in many critical engineering problems such as channel design, calculation of energy losses and sedimentation.
Ali Arman, Manochehr Fathimoghadam
doaj  

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