Results 111 to 120 of about 186,086 (280)

Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi

Advanced Science, Volume 12, Issue 37, October 6, 2025.
The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda, Kaila Petronila Medina‐Alarcón, João Paulo Soler Gonçalves Pereira, Thais Cristina dos Anjos Sevilhano, Brigitte Aguilar‐Morón, Fernando Díaz‐Cárdenas, Lucas Silva da Cruz, Francisco Humberto Xavier‐Júnior, Eduardo Festozo Vicente, João Perdigão, Beatriz G. de la Torre, Fernando Albericio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Aspergillus fumigatus and aspergillosis: From basics to clinics

Studies in Mycology, 2021
A. Arastehfar, A. Carvalho, J. Houbraken, L. Lombardi, R. Garcia-Rubio, J. Jenks, O. Rivero-Menendez, R. Aljohani, I. Jacobsen, J. Berman, N. Osherov, M. Hedayati, M. Ilkit, D. Armstrong-James, T. Gabaldón, J. Meletiadis, M. Kostrzewa, W. Pan, C. Lass‐Flörl, D. Perlin, M. Hoenigl   +20 more
semanticscholar   +1 more source

Ecology of aspergillosis: insights into the pathogenic potency of Aspergillus fumigatus and some other Aspergillus species

Microbial Biotechnology, 2016
Fungi of the genus Aspergillus are widespread in the environment. Some Aspergillus species, most commonly Aspergillus fumigatus, may lead to a variety of allergic reactions and life‐threatening systemic infections in humans. Invasive aspergillosis occurs
C. Paulussen, J. E. Hallsworth, S. Álvarez‐Pérez, W. Nierman, P. G. Hamill, D. Blain, H. Rediers, B. Lievens   +7 more
semanticscholar   +1 more source

Synthesis and Biological Evaluation of Novel 2‐(Piperidin‐4‐yl)‐1,2,3,4‐tetrahydroisoquinoline and 2‐(Piperidin‐4‐yl)decahydroisoquinoline Antimycotics

Archiv der Pharmazie, Volume 358, Issue 10, October 2025.
A series of 13 hybrid molecules of both lead structures were prepared using reductive amination as key reaction step. The antimycotic potency of the resulting compounds was evaluated against yeast and mold species. Two compounds showed remarkable potency against several yeasts, and even against Candida krusei.
Marie‐Christin Hain, Monika Klimt, Franz Bracher, Ulrike Binder, Jürgen Krauß   +4 more
wiley   +1 more source

Prevalence of cutaneous hypersensitivity to Aspergillus fumigatus in patients with asthma in the central part of Karnataka and its impact on asthma severity

Journal of Medical and Scientific Research
Introduction: Severe asthma is particularly linked to atopic conditions, especially to mold allergens like Aspergillus fumigatus. Allergic bronchopulmonary aspergillosis is an immunological lung disorder, with initial phase of hypersensitivity to ...
Bondade K, Ajit E, Raikar PS, Srinivas K, Banur A, Angadi S   +5 more
doaj   +1 more source

Exhibition of Specimens from a Case of Suppuration of the Antrum Due to Aspergillus Fumigatus, with a Short Note of the Case [PDF]

, 1913
Douglas Harmer
openalex   +1 more source

A Novel Environmental Azole Resistance Mutation in Aspergillus fumigatus and a Possible Role of Sexual Reproduction in Its Emergence

mBio, 2017
This study investigated the dynamics of Aspergillus fumigatus azole-resistant phenotypes in two compost heaps with contrasting azole exposures: azole free and azole exposed.
Jianhua Zhang, E. Snelders, B. Zwaan, Sijmen E. Schoustra, J. Meis, K. van Dijk, F. Hagen, M. T. van der Beek, G. Kampinga, J. Zoll, W. Melchers, P. Verweij, A. Debets   +12 more
semanticscholar   +1 more source

Beyond Histones: Unveiling the Functional Roles of Protein Acetylation in Prokaryotes and Eukaryotes

Cell Biology International, Volume 49, Issue 10, Page 1301-1318, October 2025.
ABSTRACT Lysine acetylation plays a crucial role in cellular processes and is found across various evolutionary organisms. Recent advancements in proteomic techniques revealed the presence of acetylation in thousands of non‐histone proteins. Here, we conducted extensive meta‐analysis of 48 acetylomes spanning diverse organisms, including archaea ...
Bruno Sousa Bonifácio, Ariely Barbosa Leite, Ana Caroline de Castro Nascimento Sousa, Suellen Rodrigues Maran, Antoniel Augusto Severo Gomes, Elton J. R. Vasconcelos, Nilmar Silvio Moretti   +6 more
wiley   +1 more source

Aspergillus Outbreak in an Intensive Care Unit: Source Analysis with Whole Genome Sequencing and Short Tandem Repeats

Journal of Fungi
Whole genome sequencing (WGS) is widely used for outbreak analysis of bacteriology and virology but is scarcely used in mycology. Here, we used WGS for genotyping Aspergillus fumigatus isolates from a potential Aspergillus outbreak in an intensive care ...
Stephan J. P. Hiel, Amber C. A. Hendriks, Jos J. A. Eijkenboom, Thijs Bosch, Jordy P. M. Coolen, Willem J. G. Melchers, Paul Anröchte, Simone M. T. Camps, Paul E. Verweij, Jianhua Zhang, Laura van Dommelen   +10 more
doaj   +1 more source

Epidemiological and genomic landscape of azole resistance mechanisms in Aspergillus fungi

Frontiers in Microbiology, 2016
Invasive aspergillosis is a life-threatening mycosis caused by the pathogenic fungus Aspergillus. The predominant causal species is Aspergillus fumigatus, and azole drugs are the treatment of choice.
Daisuke Hagiwara, Akira Watanabe, Katsuhiko Kamei, Gustavo Henrique Goldman   +3 more
doaj   +1 more source