Results 21 to 30 of about 50,941 (289)

Risk factors of severe perinatal asphyxia at tertiary hospital [PDF]

Romanian Journal of Pediatrics, 2023
Background. Perinatal asphyxia is still one of the main causes of neonatal mortality and morbidity, especially in the first week of life in developing countries.
Yayu Dwinita Jasin, Ernawati Darmawan, Martono Tri Utomo   +2 more
doaj   +1 more source

Sex Differences Between Female and Male Newborn Piglets During Asphyxia, Resuscitation, and Recovery

Frontiers in Pediatrics, 2019
Background: Male and female newborns have differences in their fetal development, fetal-to-neonatal transition, and postnatal morbidity. However, the cardiovascular fetal-to-neonatal adaption is similar between sexes.
Ramin P. La Garde, Ramin P. La Garde, Po-Yin Cheung, Po-Yin Cheung, Maryna Yaskina, Tze-Fun Lee, Megan O'Reilly, Georg M. Schmölzer, Georg M. Schmölzer   +8 more
doaj   +1 more source

Ventilation Strategies during Neonatal Cardiopulmonary Resuscitation

Frontiers in Pediatrics, 2018
Approximately, 10–20% of newborns require breathing assistance at birth, which remains the cornerstone of neonatal resuscitation. Fortunately, the need for chest compression (CC) or medications in the delivery room (DR) is rare.
Nariae Baik, Nariae Baik, Megan O’Reilly, Megan O’Reilly, Caroline Fray, Caroline Fray, Sylvia van Os, Sylvia van Os, Po-Yin Cheung, Po-Yin Cheung, Georg M. Schmölzer, Georg M. Schmölzer   +11 more
doaj   +1 more source

Return of Spontaneous Circulation Depends on Cardiac Rhythm During Neonatal Cardiac Arrest in Asphyxiated Newborn Animals

Frontiers in Pediatrics, 2021
Objective: Pulseless electrical activity (PEA) occurs in asphyxiated newborn piglets and infants. We aimed to examine whether different cardiac rhythms (asystole, bradycardia, PEA) affects the resuscitation outcomes during continuous chest compressions ...
Michael Wagner, Michael Wagner, Po-Yin Cheung, Po-Yin Cheung, Maryna Yaskina, Tze-Fun Lee, Vanessa A. Vieth, Megan O'Reilly, Megan O'Reilly, Georg M. Schmölzer, Georg M. Schmölzer, Georg M. Schmölzer   +11 more
doaj   +1 more source

Effect of birth asphyxia on neonatal blood glucose during the early postnatal life: A multi-center study in Hubei Province, China

Pediatrics and Neonatology, 2023
Background: Birth asphyxia causes hypoxia or inadequate perfusion to the organs of newborns, leading to metabolism dysfunctions including blood glucose disorders.
Chun-Hua Liu, Hong-Yan Liu, Si-Cong Peng, Sha Pan, Zhi-Ting Wan, Su-Ying Wu, Chao-Ce Fang, Rong Jiao, Wen-Xiang Wang, Bin Gan, Shu-JieYang, Ju-Fang Tan, Xiao-Fang Zhu, Ping-Li She, Qi-Hong Fan, Min Yang, Ji-Jian Xie, Jie Sun, Ling Zeng, Lian-Hong Zhang, Hui-Rong Xu, Yan-Ni Li, Ping-Feng Zhang, Wei Lu, Xian-Tao Yang, Xiong-Fei Xiao, Hong-Li Li, Zheng-Liang Rao, Chuang Gao, Ya-Hui Luo, Hong Chen, Ming-Jin Yu, Xiao-Ying Luan, Yu-Rong Huang, Shi-Wen Xia   +34 more
doaj   +1 more source

Dose-Related Pharmacokinetic and Pharmacodynamic Effects of Intramuscular Epinephrine in Healthy Neonatal Piglets

Children
Background: Epinephrine is currently the only vasopressor recommended during neonatal cardiopulmonary resuscitation (CPR). Rapid vasopressor administration is critical during CPR; however, establishing vascular access can take several minutes and ...
Marwa Ramsie, Po-Yin Cheung, Raza Hyderi, Shrieya Praveen, Tze-Fun Lee, Megan O'Reilly, Georg M. Schmölzer   +6 more
doaj   +1 more source

Pharmacokinetic and pharmacodynamic evaluation of various vasopressin doses and routes of administration in a neonatal piglet model

Scientific Reports
Epinephrine is the only recommended vasopressor during neonatal cardiopulmonary resuscitation. However, there are concerns about the potential adverse effects of epinephrine, which might hamper efficacy during cardiopulmonary resuscitation.
Marwa Ramsie, Po-Yin Cheung, Megan O’Reilly, Tze-Fun Lee, Georg M. Schmölzer   +4 more
doaj   +1 more source

Attenuation of Acute Renal Injury After the Post-resuscitation Administration of Doxycycline in Surviving Newborn Piglets With Severe Hypoxia-Reoxygenation

Frontiers in Pediatrics, 2019
Background: Asphyxiated neonates often have myocardial dysfunction and renal insufficiency. Previously we demonstrated that doxycycline improved cardio-renal function through matrix metalloproteinase (MMP)-2 inhibition in an acute swine model of neonatal
Tze-Fun Lee, Tze-Fun Lee, Min Lu, Min Lu, Matteo P. Pasquin, Matteo P. Pasquin, Georg M. Schmölzer, Georg M. Schmölzer, Po-Yin Cheung, Po-Yin Cheung, Po-Yin Cheung   +10 more
doaj   +1 more source

Peripartum Asphyxia

Veterinary Clinics of North America: Equine Practice, 1994
The abysmal survival rates for the first barking foals described more than 60 years ago were probably due to the cumulative effects of asphyxia on multiple organ systems. Successful treatment of asphyxiated foals requires recognition of periparturient conditions associated with the syndrome and appreciation of the spectrum of clinicopathologic ...
openaire   +2 more sources

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

Advanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi, Yue Qi Ong, Prativa Majee, Esther SM Wong, Amhed Missael Vargas Velazquez, Kerem Fidan, Pierce Kah‐Hoe Chow, Wai Leong Tam, Ker Kan Tan, Iain Beehuat Tan, Vinay Tergaonkar   +10 more
wiley   +1 more source