Results 51 to 60 of about 794,166 (291)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Comparison of Multiple Needle Aspirations and Open Surgical Drainage in Management of Breast Abscess

open access: yesJournal of Rawalpindi Medical College, 2009
Background: The treatment of breast abscess is a clinical dilemma which ranges from conservative treatment to surgical intervention. A recently highlighted approach is drainage of pus by needle aspiration under antibiotic cover with or without ...
Wasim Iqbal Sheikh
doaj  

Obstruction of Water Uptake in cut Chrysanthemum Stems after Dry Storage: Role of Wound-induced Increase in Enzyme Activities and Air Emboli [PDF]

open access: yes, 2009
Hydraulic conductance of cut chrysanthemum stems was lowered by the aspiration of air as well as by a wound-induced plant response. By measuring the hydraulic conductance of stem segments in which air could be introduced into and/or removed from the ...
Arevalo-Galarza, L., Meeteren, U., van
core   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Accuration of Fine Needle Aspiration Biopsy in Musculoskeletal Tumour [PDF]

open access: yes, 2016
Fine needle aspiration biopsy (FNAB) has been reported to be the preferable choice of biopsy for musculoskeletal tumour. While FNAB appears to have advantages to core biopsy in the aspect of simplicity and cost, the diagnostic accuracy should be the most
Dewo, P. (Punto)   +3 more
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Frequency of predisposing factors for the entry of foreign bodies into the ear, ingestion and aspiration in children under five years in Tabriz, 2019

open access: yesحیات, 2021
Background & Aim: Structured description of pediatric medical emergencies requires the assessment and classification of underlying factors. The aim of study was to investigate frequency of predisposing factors for the entry of foreign bodies (FB) in the ...
Ahmad Shamsi   +3 more
doaj  

A comparative study of aspiration followed by Agnikarma with aspiration in the management of ganglion - A randomized clinical trial

open access: yesIndian Journal of Health Sciences and Biomedical Research KLEU, 2015
Background: Classical texts explain the Agnikarma in detail for the management and eradication of various ailments with the limitation to understand its application and standardized methodology for each ailment.
A Amruta Wali   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

The use of Botulinum Toxin Type A in patients in out-of-hospital intensive care in Germany—results from a multidisciplinary online survey

open access: yesFrontiers in Neurology
IntroductionIn Germany, approximately 23.000 patients live in of out-of-hospital intensive care settings. About 80% suffer from neurological diseases and are prone to spasticity and sialorrhea, both of which can be effectively treated with Botulinum ...
Victoria Ohla   +3 more
doaj   +1 more source

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