Results 101 to 110 of about 370,033 (238)

Dissolvable polymeric microneedles loaded with aspirin for antiplatelet aggregation

open access: yesAsian Journal of Pharmaceutical Sciences, 2023
To reduce mucosal damage in the gastrointestinal tract caused by aspirin, we developed a dissolvable polymeric microneedle (MN) patch loaded with aspirin. Biodegradable polymers provide mechanical strength to the MNs. The MN tips punctured the cuticle of
Baorui Wang   +7 more
doaj  

Prevention is better than cure, but...: Preventive medication as a risk to ordinariness? [PDF]

open access: yes, 2011
Preventive health remains at the forefront of public health concerns; recent initiatives, such as the NHS health check, may lead to recommendations for medication in response to the identification of 'at risk' individuals. Little is known about lay views
Adams S.   +38 more
core   +1 more source

Reduction of NANOG Mediates the Inhibitory Effect of Aspirin on Tumor Growth and Stemness in Colorectal Cancer

open access: yesCellular Physiology and Biochemistry, 2017
Background/Aims: Cancer stem cells (CSCs) are considered to be responsible for tumor relapse and metastasis, which serve as a potential therapeutic target for cancer.
Hefei Wang   +24 more
doaj   +1 more source

The impact of anti-inflammatory agents on the outcome of patients with colorectal cancer [PDF]

open access: yes, 2014
Although there is increasing appreciation of the role of the host inflammatory response in determining outcome in patients in colorectal cancer, there has been little concerted effort to favourably manipulate cancer-associated inflammation, either alone ...
Horgan, P.G.   +3 more
core   +1 more source

Study of Entropy-Driven Polymorphic Stability for Aspirin Using Accurate Neural Network Interatomic Potential [PDF]

open access: yesarXiv
In this study, we present a systematic computational investigation to analyze the long debated crystal stability of two well known aspirin polymorphs, labeled as Form I and Form II. Specifically, we developed a strategy to collect training configurations covering diverse interatomic interactions between representative functional groups in the aspirin ...
arxiv  

Inferring Which Medical Treatments Work from Reports of Clinical Trials [PDF]

open access: yesarXiv, 2019
How do we know if a particular medical treatment actually works? Ideally one would consult all available evidence from relevant clinical trials. Unfortunately, such results are primarily disseminated in natural language scientific articles, imposing substantial burden on those trying to make sense of them.
arxiv  

Prevention of venous thromboembolism after hip and knee replacement among older adults [PDF]

open access: yes, 2017
BACKGROUND: Venous thromboembolism (VTE) after total hip and knee replacement is a major patient safety threat, and pharmacologic prophylaxis is generally recommended. However, clinicians disagree on the optimal prophylaxis agent.
Ko, Darae
core  

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