Results 1 to 10 of about 142,225 (311)

Delayed Rewarming Thrombocytopenia (DRT): A Temperature-Dependent Platelet Aggregation Disorder [PDF]

Hematology Reports
Below 32 °C, the second irreversible stage of platelet aggregation is absent, causing augmentation of the first reversible stage of platelet aggregation and adhesion.
Ian Joseph Cohen
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A review of natural compounds to regulate platelet aggregation: molecular mechanism and research advance [PDF]

Frontiers in Pharmacology
Platelets are a class of blood cells exfoliated from bone marrow megakaryocytes and important participants in the blood. Aggregation is a prominent part of the platelets involved in the hemostasis process, regulated by multiple signaling pathways ...
Yi Hou, Hong Li, Luochen Zhu, Yue Li, Yue Zeng, Tian Quan, Zhangqiang Xiang, Yue Zhang, Yuan Bian, Yuxun Wei   +9 more
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Macrostachyols A-D, oligostilbenes from Gnetum macrostachyum inhibited in vitro human platelet aggregation [PDF]

Journal of HerbMed Pharmacology, 2021
Introduction: Gnetum macrostachyum is a known Thai medicinal plant as a source of bioactive oligostilbenes, which possess platelet inhibitory activities.
Serm Surapinit, Nuttakorn Baisaeng
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Ex vivo STUDY OF THE ACTION OF INTEGRIN RECEPTORS ANTAGONIST FROM ECHIS MULTISQUAMATIS SNAKE VENOM ON PLATELETS OF PREGNANT WOMEN WITH COMPICATIONS DURING GESTATION [PDF]

Biotechnologia Acta, 2023
Aim. In our work, we studied platelet aggregation in blood plasma of pregnant women and estimated the possibility of ex vivo normalization of aggregation rate using a polypeptide from the Echis multisquamatus snake venom.
O. M. PLATONOV, I. V. US
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The Ratio of ADP- to TRAP-Induced Platelet Aggregation Quantifies P2Y12-Dependent Platelet Inhibition Independently of the Platelet Count. [PDF]

PLoS ONE, 2016
This study aimed to assess the association of clinical factors with P2Y12-dependent platelet inhibition as monitored by the ratio of ADP- to TRAP-induced platelet aggregation and conventional ADP-induced aggregation, respectively.Controversial findings ...
Christoph B Olivier, Melanie Meyer, Hans Bauer, Katharina Schnabel, Patrick Weik, Qian Zhou, Christoph Bode, Martin Moser, Philipp Diehl   +8 more
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Correlation Between P-Selectin Level and Platelet Aggregation in Cerebral Venous Sinus Thrombosis Patients

Majalah Kedokteran Bandung, 2023
One of the causes of cerebral venous sinus thrombosis (CVST) is platelet hyperactivity. Adhesion and secretion are the beginning of platelet activation, which is indicated by a change in the Platelet-selectin (P-selectin) level.
Rahmawati Nurmin, Leni Lismayanti, Tiene Rostini, Agnes Rengga Indrati, Lisda Amalia   +4 more
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Quinonoid dihydropteridine reductase, a tetrahydrobiopterin-recycling enzyme, contributes to 5-hydroxytryptamine-associated platelet aggregation in mice

Journal of Pharmacological Sciences, 2022
Quinonoid dihydropteridine reductase (QDPR) regenerates tetrahydrobiopterin (BH4), which is an essential cofactor for catecholamine and serotonin (5-hydroxytryptamine, 5-HT) biosynthesis.
Yui Suganuma, Chiho Sumi-Ichinose, Taiki Kano, Kazuhisa Ikemoto, Taei Matsui, Hiroshi Ichinose, Kazunao Kondo   +6 more
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Optimized tool for evaluation of platelet function measured by impedance aggregometry

Platelets, 2021
Platelet aggregation measured by impedance aggregometry is highly dependent on platelet count. We previously developed a tool to interpret impedance aggregometry based on the strong linear correlation between platelet counts and platelet aggregation at ...
Anna Schultz-Lebahn, Mette Tiedemann Skipper, Anne-Mette Hvas, Ole Halfdan Larsen   +3 more
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Thrombin-induced platelet aggregation −effect of dabigatran using automated platelet aggregometry−

Platelets, 2020
Dabigatran, a direct oral thrombin inhibitor, has two therapeutic effects: anticoagulation; and antiplatelet activity. In the clinical field, evaluation of the effect of dabigatran on thrombin-induced platelet aggregation is difficult because of fibrin ...
Mie Shimizu, Tatsunori Natori, Keisuke Tsuda, Makiko Yoshida, Asami Kamada, Kiyotaka Oi, Yoko Ishigaku, Kazumasa Oura, Shinsuke Narumi, Masahiro Yamamoto, Yasuo Terayama   +10 more
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The extracellular Ero1α/PDI electron transport system regulates platelet function by increasing glutathione reduction potential

Redox Biology, 2022
Protein disulfide isomerase (PDI), an oxidoreductase, possesses two vicinal cysteines in the -Cys-Gly-His-Cys-motif that either form a disulfide bridge (S–S) or exist in a sulfhydryl form (-SH), forming oxidized or reduced PDI, respectively. PDI has been
Lu Wang, Xi Wang, Xiying Lv, Qiushuo Jin, Hongcai Shang, Chih-chen Wang, Lei Wang   +6 more
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