Results 1 to 10 of about 7,899,636 (253)

Flow cytometry-based platelet function testing is predictive of symptom burden in a cohort of bleeders

Platelets, 2018
Platelet function disorders (PFDs) are common in patients with mild bleeding disorders (MBDs), yet the significance of laboratory findings suggestive of a PFD remain unclear due to the lack of evidence for a clinical correlation between the test results ...
Niklas Boknäs, Sofia Ramström, Lars Faxälv, Tomas L. Lindahl   +3 more
doaj   +1 more source

Inconsistency of different methods for assessing ex vivo platelet function: relevance for the detection of aspirin resistance

Haematologica, 2010
Background Assays to evaluate platelet function are often interchangeably used to assess “resistance” to aspirin. We compared different platelet function assays in patients treated or untreated with aspirin.Design and Methods Platelet function was ...
Giulia Renda, Maria Zurro, Gelsomina Malatesta, Benedetta Ruggieri, Raffaele De Caterina   +4 more
doaj   +1 more source

Aspirin and clopidogrel resistance: methodological challenges and opportunities

Vascular Health and Risk Management, 2010
Armen Yuri GasparyanClinical Research Unit, Russell’s Hall Hospital, Dudley Group of Hospitals NHS Foundation Trust, West Midlands, UKAbstract: Antiplatelet drug resistance is one of the urgent issues in current cardiovascular medicine.
Armen Yuri Gasparyan
doaj  

Arachidonic acid causes lysis of blood cells and ADP-dependent platelet activation responses in platelet function tests

Platelets, 2019
The use of arachidonic acid (AA) to stimulate platelets is considered as a specific approach to study aspirin treatment efficacy. However, very high concentrations of AA are used, and it has been previously reported that AA can induce cell lysis in other
Sofia Ramström
doaj   +1 more source

Thrombopoietin and platelet aggregation in patients with stable coronary artery disease

Platelets, 2017
Thrombopoietin (TPO) may facilitate platelet activation and aggregation. However, data on the impact of TPO on platelet aggregation in patients with stable coronary artery disease (CAD) are scarce.
Sanne Bøjet Larsen, Erik Lerkevang Grove, Søs Neergaard-Petersen, Morten Würtz, Anne-Mette Hvas, Steen Dalby Kristensen   +5 more
doaj   +1 more source

A modified microchip-based flow chamber system for evaluating thrombogenicity in patients with thrombocytopenia

Thrombosis Journal, 2020
Background In the intensive care unit (ICU), patients with thrombocytopenia are at high risk for bleeding and should be assessed for their thrombogenic potential.
Bengo Atari, Takashi Ito, Tomoka Nagasato, Tomoko Ohnishi, Kazuya Hosokawa, Tomotsugu Yasuda, Ikuro Maruyama, Yasuyuki Kakihana   +7 more
doaj   +1 more source

Comparison of platelet function tests for the in vitro quality assessment of platelet concentrates produced under real-life conditions

Platelets, 2019
Platelet quality in different platelet concentrates (PCs) has been the subject of several studies. Nonetheless, there is a lack of robust data on the correlation and agreement among platelet function tests as a prerequisite for the association of PC ...
Lars Asmis, Anja Moldenhauer, Walter Hitzler, Peter Hellstern   +3 more
doaj   +1 more source

The Incidence and Methods for Detecting Aspirin Resistance in Pediatric Patients

Pediatric Health, Medicine and Therapeutics
Hansamon Poparn,1,2 Yaowaree Kittikalayawong,1,2 Piti Techavichit,1,2 Supanun Lauhasurayotin,1,2 Kanhatai Chiengthong,1,2 Phumin Chaweephisal,2 Darintr Sosothikul1,2 1Division of Pediatric Hematology and Oncology, Department of Pediatrics, Faculty of ...
Poparn H, Kittikalayawong Y, Techavichit P, Lauhasurayotin S, Chiengthong K, Chaweephisal P, Sosothikul D   +6 more
doaj  

Platelet and Fibrinogen Contribution to Clot Strength in Premature Neonates with Sepsis

Children
Background/Objectives: Platelet transfusions are administered to preterm neonates with thrombocytopenia prophylactically to decrease their bleeding risk.
Dimitra Gialamprinou, Christos-Georgios Kontovazainitis, Abraham Pouliakis, Alexandra Fleva, Anastasia Giannakou, Elisavet Diamanti, Panagiotis Kratimenos, Georgios Mitsiakos   +7 more
doaj   +1 more source

Markers for platelet function testing by flow cytometry: where are we now? A clinical perspective

Research and Practice in Thrombosis and Haemostasis
Flow cytometry is transforming platelet function testing by offering high sensitivity, low sample requirements, and compatibility with thrombocytopenic and pediatric specimens.
Benjamin E.J. Spurgeon
doaj   +1 more source