Results 21 to 30 of about 170,471 (154)

The application value of determination of hemostasis and thrombosis in tumor patients [PDF]

Zhenduanxue lilun yu shijian, 2023
Abnormal coagulation function is an important feature of the occurrence and development of malignant tumors. Tumor cells release pro-angiogenic factors that cause vascular endothelial damage and induce platelet activation and proliferation, all of which ...
WANG Yanchun, LU Renquan
doaj   +1 more source

Platelet function tests: A 5-year audit of platelet function tests done for bleeding disorders in a tertiary care center of a developing country

Indian Journal of Pathology and Microbiology, 2018
Introduction: The platelet function disorders remain largely undiagnosed or incompletely diagnosed in developing nations due to lack of availability of tests like lumiaggregometry, granule release assay or molecular testing.
Sabina Langer, Jasmita Dass, Amrita Saraf, Jyoti Kotwal   +3 more
doaj   +1 more source

Reduced platelet function in preterm neonates compared with term neonates

Research and Practice in Thrombosis and Haemostasis, 2022
Background A reduced platelet function might contribute to the longer bleeding time seen in preterm neonates. However, the previously used platelet function testing in neonates is limited due to methodological limitations, mainly caused by difficulties ...
Nadia Thrane Hovgesen, Claus V. B. Hviid, Alexander K. Grevsen, Anne Kirkeby Hansen, Anne‐Mette Hvas   +4 more
doaj   +1 more source

Sticky Platelet Syndrome in Patients with Uninduced Venous Thrombosis

Turkish Journal of Hematology, 2013
OBJECTIVE: Sticky platelet syndrome (SPS) is a common autosomal dominant inherited platelet disorder. SPS is characterized by platelet hyperreactivity and is associated with arterial and venous thrombosis.
Emre Tekgündüz, Muzaffer Demir, Seval Akpınar, Alev Akyol Erikçi, Erman Öztürk, Onur Kırkızlar   +5 more
doaj   +1 more source

Platelet Contribution to Clot Strength in Thromboelastometry: Count, Function, or Both?

Platelets, 2020
In thromboelastometry (ROTEMTM) the difference in amplitude between the EXTEM and the FIBTEM is considered an index of platelet contribution to clot strength (PCSamp). The difference in elasticity (PCSel) is rarely used.
Marco Ranucci, Umberto Di Dedda, Ekaterina Baryshnikova   +2 more
doaj   +1 more source

Platelet Function and Genetic Testing

Journal of the American College of Cardiology, 2013
#### Perspective: Platelet and Genetic Testing for Clopidogrel Hyporesponsiveness Use as a Research Tool Dr. Angiolillo has received payment as an individual for consulting fee or honorarium from Bristol-Myers Squibb, Sanofi-Aventis, Eli Lilly, Daiichi Sankyo, The Medicines Company, AstraZeneca,
Angiolillo, Dominick J., Ferreiro, José Luis, Price, Matthew J., Kirtane, Ajay J., Stone, Gregg W.   +4 more
openaire   +2 more sources

Platelet Function Assays for the Diagnosis of Aspirin Resistance

Platelets, 2022
Aspirin, an antiplatelet drug, is commonly used at low doses for numerous indications, including prophylaxis of cardiovascular, neurovascular, and venous thromboembolic events.
Nameer Van Oosterom, Michael Barras, Neil Cottrell, Robert Bird   +3 more
doaj   +1 more source

Evaluation of an automated light transmission aggregometry

Platelets, 2017
Light transmission aggregometry (LTA) is the “gold standard” for platelet function assessment, but it is time-consuming and labor intensive. Recently, an automated platelet aggregation method has been developed on a routine coagulation analyzer (Sysmex ...
Li-qin Ling, Juan Liao, Qian Niu, Xia Wang, Jin Jia, Cheng-hua Zuo, Hong Jiang, Jing Zhou   +7 more
doaj   +1 more source

Platelet Function Testing in Cardiovascular Diseases [PDF]

Circulation, 2004
Case presentation 1: Mr F. is a 60-year-old man with unstable angina who takes aspirin, 81 mg/day. A platelet function test demonstrates that his platelets are “resistant” to aspirin. Should his treatment be changed? Case presentation 2: Mr K. is a 60-year-old man with unstable angina who takes aspirin, 81 mg/day, and clopidogrel, 75 mg/day.
openaire   +5 more sources

Impaired platelet function in Hermansky-Pudlak syndrome associated with novel mutations in HPS3, HPS6 and HPS8 genes

Bleeding, Thrombosis and Vascular Biology
We report three unrelated cases of Hermansky-Pudlak (HP) characterized by novel mutations in HPS3 (compound heterozygosity for c.1457G>A and c.1813G>T), HPS6 (homozygous c.210_211insGGGCC), and HPS8 (homozygous c.299dupC in BLOC1S3) genes.
Lisa Pieri, Silvia Linari, Francesca Salvianti, Monica Attanasio, Giancarlo Castaman   +4 more
doaj   +1 more source