Results 21 to 30 of about 274,208 (297)

Platelet Function Tests: Why They Fail to Guide Personalized Antithrombotic Medication [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2015
Diana A. Gorog, Young‐Hoon Jeong
doaj   +2 more sources

Platelet function in overt hypothyroidism

Journal of Applied Hematology, 2021
BACKGROUND: Hypothyroidism is associated with a shift of the hemostatic system to a hypocoagulable state and inhibited platelet function. However, previous studies did not consider the different degrees of response to thyroxine treatment and its effect ...
Abeer Khalid Al-Ghumlas, Aishah Ali Ekhzaimy, Abdel Galil Mohammad Abdel Gader   +2 more
doaj   +1 more source

Platelet Mechanobiology Inspired Microdevices: From Hematological Function Tests to Disease and Drug Screening

Frontiers in Pharmacology, 2022
Platelet function tests are essential to profile platelet dysfunction and dysregulation in hemostasis and thrombosis. Clinically they provide critical guidance to the patient management and therapeutic evaluation.
Yingqi Zhang, Yingqi Zhang, Yingqi Zhang, Fengtao Jiang, Yunfeng Chen, Yunfeng Chen, Lining Arnold Ju, Lining Arnold Ju, Lining Arnold Ju   +8 more
doaj   +1 more source

Optimized tool for evaluation of platelet function measured by impedance aggregometry

Platelets, 2021
Platelet aggregation measured by impedance aggregometry is highly dependent on platelet count. We previously developed a tool to interpret impedance aggregometry based on the strong linear correlation between platelet counts and platelet aggregation at ...
Anna Schultz-Lebahn, Mette Tiedemann Skipper, Anne-Mette Hvas, Ole Halfdan Larsen   +3 more
doaj   +1 more source

Platelet Phenotyping and Function Testing in Thrombocytopenia [PDF]

Journal of Clinical Medicine, 2021
Patients who suffer from inherited or acquired thrombocytopenia can be also affected by platelet function defects, which potentially increase the risk of severe and life-threatening bleeding complications. A plethora of tests and assays for platelet phenotyping and function analysis are available, which are, in part, feasible in clinical practice due ...
Kerstin Jurk, Yavar Shiravand
openaire   +2 more sources

Clinical utility of remote platelet function measurement using P-selectin: assessment of aspirin, clopidogrel, and prasugrel and bleeding disorders [PDF]

, 2018
Vascular diseases such as myocardial infarction and ischemic stroke are associated with increased platelet function whilst the risk of recurrence is reduced by antiplatelet agents such as aspirin, clopidogrel, and prasugrel.
Adamany J, Bath PM, May J, Flaherty K, Woodhouse LJ, Dovlatova N, Fox SC, England TJ, Krishnan K, Robinson TG, Sprigg N, et al., Bath PM, Woodhouse LJ, Appleton JP, Beridze M, Christensen H, Dineen RA, Duley L, England TJ, Flaherty K, Havard D, et al., Cardoso RN, Benjo AM, DiNicolantonio JJ, Garcia DC, Macedo FY, El-Hayek G, Nadkarni GN, Gili S, Iannaccone M, Konstantinidis I, et al., Dovlatova N, Fox SC, May JA, Dovlatova N, Glenn JR, Johnson A, White AE, Radhakrishnan A, Heptinstall S., Heptinstall S, Heptinstall S, Heptinstall S, Jane May, Laohathai P, Joshi R, Radhakrishnan A, May J, Dovlatova N, Heptinstall S, Fox S., May J, Philip M Bath, Stan Heptinstall, TARDIS Trial Investigators, Krishnan K, Beridze M, Christensen H, Dineen R, Duley L, Heptinstall S, James M, Markus H, Pocock S, et al., Vlachojannis G   +15 more
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Platelet Function Tests [PDF]

Seminars in Thrombosis and Hemostasis, 2016
Traditionally developed for diagnosis of bleeding disorders, platelet function assays have become increasingly used in basic research on platelet physiology, in phenotype-genotype associations in bleeding disorders, in drug development as surrogate endpoints of efficacy of new antiplatelet therapy, and to an extent, in the monitoring of antiplatelet ...
openaire   +3 more sources

Presence of factors that activate platelet aggregation in mitral stenotic patients' plasma [PDF]

, 2005
Background Although the association between mitral stenosis (MS) and increased coagulation activity is well recognized, it is unclear whether enhanced coagulation remains localized in the left atrium or whether this represents a systemic problem.
Istemihan Tengiz, Ertugrul Ercan, Fahri Sahin, Emin Alioglu, Can Duman, Guray Saydam, Filiz Buyukkececi, CW Chiang, HA Fleming, R Atak, M Ileri, RE Peverill, K Yamamoto, FL Li-Saw-Hee, DJ Sahn, L Hatle, I Hayashi, M Yasaka, KA Bauer, MD Boisclair, D Tschoepe, J Maly, J Bonnar, JJ Hwang, G Pongratz, S Rohmann, S Kamath   +26 more
core   +3 more sources

The importance of tests applied to evaluate the effectiveness of antiplatelet therapy in patients with recurrent coronary stent thrombosis [PDF]

, 2009
Background. Stent thrombosis is potentially lethal complication with huge economic burden. The role of insufficient response to antiplatelet therapy is still unclear reason for its occurrence. Case report.
Cikota Bojana, Grdinić Aleksandra, Ilić Vesna, Magić Zvonko, Majstorović Ivana, Miljić Predrag, Obradović Slobodan, Ostojić Miodrag, Radovanović Mina, Vojvodić Danilo, Đukanović Nina   +10 more
core   +1 more source

Stability and utility of flow cytometric platelet activation tests: A modality to bridge the gap between diagnostic demand and supply

Platelets, 2022
Light transmission aggregometry (LTA) is the gold standard for the diagnosis of platelet function disorders (PFDs). The requirement of customized aggregometer, large blood volume, normal platelet count and processing within 4 hours of venipuncture for ...
Rutvi Gautam Dave, Tulasi Geevar, Gayathiri Kaduvetti Chellaiya, Joy John Mammen, Ramya Vijayan, Ashok Samuel, Mahasampath Gowri, Sukesh Chandran Nair   +7 more
doaj   +1 more source