Results 21 to 30 of about 7,899,636 (253)

Anti-platelet therapy: ADP receptor antagonists. [PDF]

, 2011
The P2Y(12) receptor on platelets with which ADP interacts has an important role in promoting platelet function and thereby platelet involvement in both haemostasis and thrombosis.
Heptinstall, S, Wijeyeratne, YD, Stan Heptinstall, Yanushi Dullewe Wijeyeratne   +3 more
core   +1 more source

Long-term treated HIV infection is associated with platelet mitochondrial dysfunction

Scientific Reports, 2021
HIV infection and antiretroviral therapy have been linked to mitochondrial dysfunction. The role of platelet mitochondrial dysfunction in thrombosis, immunoregulation and age-related diseases is increasingly appreciated.
Wouter A. van der Heijden, Lisa van de Wijer, Martin Jaeger, Karin Grintjes, Mihai G. Netea, Rolf T. Urbanus, Reinout van Crevel, Lambertus P. van den Heuvel, Maaike Brink, Richard J. Rodenburg, Philip G. de Groot, Andre J. van der Ven, Quirijn de Mast   +12 more
doaj   +1 more source

The application value of determination of hemostasis and thrombosis in tumor patients [PDF]

Zhenduanxue lilun yu shijian, 2023
Abnormal coagulation function is an important feature of the occurrence and development of malignant tumors. Tumor cells release pro-angiogenic factors that cause vascular endothelial damage and induce platelet activation and proliferation, all of which ...
WANG Yanchun, LU Renquan
doaj   +1 more source

Platelet function tests: A 5-year audit of platelet function tests done for bleeding disorders in a tertiary care center of a developing country

Indian Journal of Pathology and Microbiology, 2018
Introduction: The platelet function disorders remain largely undiagnosed or incompletely diagnosed in developing nations due to lack of availability of tests like lumiaggregometry, granule release assay or molecular testing.
Sabina Langer, Jasmita Dass, Amrita Saraf, Jyoti Kotwal   +3 more
doaj   +1 more source

Reduced platelet function in preterm neonates compared with term neonates

Research and Practice in Thrombosis and Haemostasis, 2022
Background A reduced platelet function might contribute to the longer bleeding time seen in preterm neonates. However, the previously used platelet function testing in neonates is limited due to methodological limitations, mainly caused by difficulties ...
Nadia Thrane Hovgesen, Claus V. B. Hviid, Alexander K. Grevsen, Anne Kirkeby Hansen, Anne‐Mette Hvas   +4 more
doaj   +1 more source

Sticky Platelet Syndrome in Patients with Uninduced Venous Thrombosis

Turkish Journal of Hematology, 2013
OBJECTIVE: Sticky platelet syndrome (SPS) is a common autosomal dominant inherited platelet disorder. SPS is characterized by platelet hyperreactivity and is associated with arterial and venous thrombosis.
Emre Tekgündüz, Muzaffer Demir, Seval Akpınar, Alev Akyol Erikçi, Erman Öztürk, Onur Kırkızlar   +5 more
doaj   +1 more source

Platelet Contribution to Clot Strength in Thromboelastometry: Count, Function, or Both?

Platelets, 2020
In thromboelastometry (ROTEMTM) the difference in amplitude between the EXTEM and the FIBTEM is considered an index of platelet contribution to clot strength (PCSamp). The difference in elasticity (PCSel) is rarely used.
Marco Ranucci, Umberto Di Dedda, Ekaterina Baryshnikova   +2 more
doaj   +1 more source

Platelet Function and Genetic Testing

Journal of the American College of Cardiology, 2013
#### Perspective: Platelet and Genetic Testing for Clopidogrel Hyporesponsiveness Use as a Research Tool Dr. Angiolillo has received payment as an individual for consulting fee or honorarium from Bristol-Myers Squibb, Sanofi-Aventis, Eli Lilly, Daiichi Sankyo, The Medicines Company, AstraZeneca,
Angiolillo, Dominick J., Ferreiro, José Luis, Price, Matthew J., Kirtane, Ajay J., Stone, Gregg W.   +4 more
openaire   +2 more sources

Platelet preparation for function testing in the laboratory and clinic: Historical and practical aspects

Research and Practice in Thrombosis and Haemostasis, 2019
Laboratory tests of platelet function are instrumental in studying platelet physiology and inherited or acquired platelet abnormalities. Light transmission aggregometry, developed in the early 1960s, is still considered the gold standard for the ...
Béatrice Hechler, Arnaud Dupuis, Pierre H. Mangin, Christian Gachet   +3 more
doaj   +1 more source

Platelet Function Assays for the Diagnosis of Aspirin Resistance

Platelets, 2022
Aspirin, an antiplatelet drug, is commonly used at low doses for numerous indications, including prophylaxis of cardiovascular, neurovascular, and venous thromboembolic events.
Nameer Van Oosterom, Michael Barras, Neil Cottrell, Robert Bird   +3 more
doaj   +1 more source