Results 41 to 50 of about 170,471 (154)

Effects of pH and concentration of sodium citrate anticoagulant on platelet aggregation measured by light transmission aggregometry induced by adenosine diphosphate

Platelets, 2018
The 2013 ISTH-SSC guidelines for the standardization of light transmission aggregometry (LTA) were largely based on expert consensus, as studies directly comparing LTA methodologies were lacking.
Ksenia Germanovich, Eti Alessandra Femia, Chun Yan Cheng, Natalia Dovlatova, Marco Cattaneo   +4 more
doaj   +1 more source

Platelet function tests using platelet aggregometry: need for repetition of the test for diagnosis of defective platelet function

Platelets, 2003
Four hundred and ninety seven patients were referred to our center for platelet aggregation studies because of spontaneous mucocutaneous bleeds. All these patients had normal complete blood count, platelet count and peripheral smears except in ten patients of Bernard Soulier Syndrome where platelet count was marginally reduced in the presence of giant ...
K, Ghosh, S, Nair, B, Kulkarni, A, Khare, S, Shetty, D, Mohanty   +5 more
openaire   +2 more sources

Study of liver function test, renal function test and platelet count in hypertensive disorders of pregnancy [PDF]

New Indian Journal of OBGYN
Background: The World Health Organization (WHO) systematically reviews maternal mortality worldwide, and in developed countries, 16 percent of maternal deaths were due to hypertensive disorders.
Indrani R, Chandana Ray Das
doaj   +1 more source

Investigation of the contribution of an underlying platelet defect in women with unexplained heavy menstrual bleeding

Platelets, 2019
Heavy menstrual bleeding (HMB) is often undiagnosed in women and can cause discomfort and distress. A haemostatic cause for excessive bleeding is often not routinely investigated and can lead to hysterectomy at an early age.
Gillian C. Lowe, Roksana Fickowska, Rashid Al Ghaithi, Annabel Maclachlan, Paul Harrison, Will Lester, Steve P. Watson, Bethan Myers, Justin Clark, Neil V. Morgan   +9 more
doaj   +1 more source

Inconsistency of different methods for assessing ex vivo platelet function: relevance for the detection of aspirin resistance

Haematologica, 2010
Background Assays to evaluate platelet function are often interchangeably used to assess “resistance” to aspirin. We compared different platelet function assays in patients treated or untreated with aspirin.Design and Methods Platelet function was ...
Giulia Renda, Maria Zurro, Gelsomina Malatesta, Benedetta Ruggieri, Raffaele De Caterina   +4 more
doaj   +1 more source

Flow cytometry-based platelet function testing is predictive of symptom burden in a cohort of bleeders

Platelets, 2018
Platelet function disorders (PFDs) are common in patients with mild bleeding disorders (MBDs), yet the significance of laboratory findings suggestive of a PFD remain unclear due to the lack of evidence for a clinical correlation between the test results ...
Niklas Boknäs, Sofia Ramström, Lars Faxälv, Tomas L. Lindahl   +3 more
doaj   +1 more source

Aspirin and clopidogrel resistance: methodological challenges and opportunities

Vascular Health and Risk Management, 2010
Armen Yuri GasparyanClinical Research Unit, Russell’s Hall Hospital, Dudley Group of Hospitals NHS Foundation Trust, West Midlands, UKAbstract: Antiplatelet drug resistance is one of the urgent issues in current cardiovascular medicine.
Armen Yuri Gasparyan
doaj  

Arachidonic acid causes lysis of blood cells and ADP-dependent platelet activation responses in platelet function tests

Platelets, 2019
The use of arachidonic acid (AA) to stimulate platelets is considered as a specific approach to study aspirin treatment efficacy. However, very high concentrations of AA are used, and it has been previously reported that AA can induce cell lysis in other
Sofia Ramström
doaj   +1 more source

Platelet function testing in uraemic patients

Hematology, 2008
Chronic renal failure (CRF) is associated with excessive bleeding for a variety of reasons. Platelet dysfunction is probably the most consistent and important feature, particularly platelet-platelet and platelet-vessel wall interactions. The skin bleeding time (SBT) is the best established predictor of bleeding in uraemic patients but suffers from poor
Shir-Jing, Ho, Rosalie, Gemmell, Timothy A, Brighton   +2 more
openaire   +2 more sources

Thrombopoietin and platelet aggregation in patients with stable coronary artery disease

Platelets, 2017
Thrombopoietin (TPO) may facilitate platelet activation and aggregation. However, data on the impact of TPO on platelet aggregation in patients with stable coronary artery disease (CAD) are scarce.
Sanne Bøjet Larsen, Erik Lerkevang Grove, Søs Neergaard-Petersen, Morten Würtz, Anne-Mette Hvas, Steen Dalby Kristensen   +5 more
doaj   +1 more source