Platelet Contribution to Clot Strength in Thromboelastometry: Count, Function, or Both?
In thromboelastometry (ROTEMTM) the difference in amplitude between the EXTEM and the FIBTEM is considered an index of platelet contribution to clot strength (PCSamp). The difference in elasticity (PCSel) is rarely used.
Marco Ranucci +2 more
doaj +1 more source
Hematologic, hepatic, and renal function changes in hospitalized patients with Middle East respiratory syndrome coronavirus [PDF]
Background There are no longitudinal data on the changes in hematologic, hepatic, and renal function findings in patients with Middle East respiratory syndrome coronavirus (MERS‐CoV) infection. Methods This is a retrospective cohort study of 16 MERS‐
Abbasi, S. +5 more
core +1 more source
Platelet Function and Genetic Testing
#### Perspective: Platelet and Genetic Testing for Clopidogrel Hyporesponsiveness Use as a Research Tool Dr. Angiolillo has received payment as an individual for consulting fee or honorarium from Bristol-Myers Squibb, Sanofi-Aventis, Eli Lilly, Daiichi Sankyo, The Medicines Company, AstraZeneca,
Angiolillo, Dominick J. +4 more
openaire +2 more sources
Platelet Function Assays for the Diagnosis of Aspirin Resistance
Aspirin, an antiplatelet drug, is commonly used at low doses for numerous indications, including prophylaxis of cardiovascular, neurovascular, and venous thromboembolic events.
Nameer Van Oosterom +3 more
doaj +1 more source
Effects of High Flavanol Dark Chocolate on Cardiovascular Function and Platelet Aggregation. [PDF]
Regular consumption of chocolate and cocoa products has been linked to reduced cardiovascular mortality. This study compared the effects of high flavanol dark chocolate (HFDC; 1064mg flavanols/day for 6 weeks) and low flavanol dark chocolate (LFDC; 88mg ...
Akita +56 more
core +1 more source
Diagnosis of von Willebrand disease in Argentina: a single institution experience [PDF]
von Willebrand disease (VWD) is the most common autosomal bleeding disorder, mostlyinherited as dominant trait. VWD is due to deficiency/abnormality of von Willebrand factor (VWF).
Blanco, Alicia Noemi +5 more
core +1 more source
Platelet Biochemistry and Morphology after Cryopreservation [PDF]
Platelet cryopreservation has been investigated for several decades as an alternative to room temperature storage of platelet concentrates. The use of dimethylsulfoxide as a cryoprotectant has improved platelet storage and cryopreserved concentrates can ...
Compernolle, Veerle +2 more
core +1 more source
Evaluation of an automated light transmission aggregometry
Light transmission aggregometry (LTA) is the “gold standard” for platelet function assessment, but it is time-consuming and labor intensive. Recently, an automated platelet aggregation method has been developed on a routine coagulation analyzer (Sysmex ...
Li-qin Ling +7 more
doaj +1 more source
Potentiation of thrombus instability: a contributory mechanism to the effectiveness of antithrombotic medications [PDF]
© The Author(s) 2018The stability of an arterial thrombus, determined by its structure and ability to resist endogenous fibrinolysis, is a major determinant of the extent of infarction that results from coronary or cerebrovascular thrombosis.
A Gast +66 more
core +2 more sources
We report three unrelated cases of Hermansky-Pudlak (HP) characterized by novel mutations in HPS3 (compound heterozygosity for c.1457G>A and c.1813G>T), HPS6 (homozygous c.210_211insGGGCC), and HPS8 (homozygous c.299dupC in BLOC1S3) genes.
Lisa Pieri +4 more
doaj +1 more source

