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PlateletsThe last decade has seen increasing use of advanced imaging techniques in platelet research. However, there has been a lag in the development of image analysis methods, leaving much of the information trapped in images.
Abigail S. McGovern +7 more
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Frontiers in Bioengineering and Biotechnology, 2022 Lyophilized platelets have been explored as a potential hemostatic agent due to their long-term ambient storage capabilities that make them readily available in various scenarios.
Brian Schnoor, Anne-Laure Papa
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Медицинская иммунология, 2018 Platelets are the smallest blood cells, and yet their total volume and surface area exceed those of all types of leukocytes combined. Platelets are produced by the bone marrow megakaryocytes and megakaryocytes in the lung microvessels.
N. B. Serebryanaya +3 more
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Disparate effects of adhesion and degranulation of platelets on myocardial and coronary function in postischaemic hearts [PDF]
, 1998 Beside the major effect of acute thrombus formation, little is known about the interaction of platelets with the coronary endothelium in an ischaemia–reperfusion situation.
Welsch, Ulrich +3 more
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Protocol for Murine/Mouse Platelets Isolation and Their Reintroduction in vivo
Bio-Protocol, 2017 Platelets and coagulation have long been known to be essential for metastasis in experimental models. In order to study the interactions between tumor cells, platelets and endothelium, we have adapted methods used in coagulation research for the ...
Jae Im, Ruth Muschel
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Humanized mouse models for inherited thrombocytopenia studies
Platelets, 2023 Inherited thrombocytopenia (IT) is a group of hereditary disorders characterized by a reduced platelet count as the main clinical manifestation, and often with abnormal platelet function, which can subsequently lead to impaired hemostasis.
Xiaojie Wang +13 more
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Platelets, 2022 MYH9-related disorder (MYH9-RD) is autosomal dominant thrombocytopenia caused by mutations in the MYH9 gene, which codes for the non-muscle myosin-IIA heavy chain. We present a case of a 24-year-old Chinese man with MYH9-RD who was initially misdiagnosed
Abdul Rehman Arif +5 more
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Platelet kinetics in the pulmonary microcirculation in vivo assessed by intravital microscopy [PDF]
, 2002 Growing evidence supports the substantial pathophysiological impact of platelets on the development of acute lung injury. Methods for studying these cellular mechanisms in vivo are not present yet.
Eichhorn, M. E. +3 more
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Differential expression of exosomal microRNAs in fresh and senescent apheresis platelet concentrates
Platelets, 2022 Patients have a high risk of suffering adverse reactions after receiving platelet products stored for 5 days. Bioactive exosomes in platelet products can be accumulated during storage, which is associated with adverse reactions.
Ziyue Mi +7 more
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Platelets, 2022 While several small studies have found that selenium deficiency is associated with low platelet counts, they lack generalizability. We used data from the National Health and Nutrition Examination Surveys collected over a 12-year period.
Neda Rehan, Rehan Qayyum
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