Results 11 to 20 of about 432,603 (317)

Platelets and Platelet Phosphatides in Uremia [PDF]

open access: yesBlood, 1960
Abstract 1. The platelets of 20 uremic subjects were studied, utilizing the following procedures; phase platelet count, serum prothrombin time, thromboplastin generation test with evaluation of plasma, serum, and platelet reagents. 2.
G, ALTSCHULER, A J, MARCUS, H L, ULLMAN
openaire   +2 more sources

Young steady-state rabbit platelets do not have an enhanced capacity to expose procoagulant phosphatidylserine

open access: yesPlatelets, 2018
Platelets are recognized to be physiologically and functionally heterogeneous. An example of the diversity in reactivity is the formation of a distinct subpopulation of procoagulant phosphatidylserine (PS)-exposing platelets upon activation. Platelet age
Emily C. Reddy   +4 more
doaj   +1 more source

Gender-related differences in changes of estimated bleeding risk in patients on dual antiplatelet therapy: the RE-SCORE multicenter prospective registry

open access: yesPlatelets, 2022
The risk of bleeding as predicted by the PRECISE-DAPT score can vary over time after percutaneous coronary intervention (PCI). We sought to compare the predictive ability of the PRECISE-DAPT score calculated at baseline and reassessed during follow-up in
Francesco Pelliccia   +10 more
doaj   +1 more source

Compartmentalized megakaryocyte death generates functional platelets committed to caspase-independent death [PDF]

open access: yes, 2003
Caspase-directed apoptosis usually fragments cells, releasing nonfunctional, prothrombogenic, membrane-bound apoptotic bodies marked for rapid engulfment by macrophages.
Jones, David B.   +9 more
core   +1 more source

Diagnostic and prognostic role of platelets in patients with sepsis and septic shock

open access: yesPlatelets, 2023
Studies investigating the prognostic role of platelets commonly include critically ill patients, whereas data regarding the prognostic impact of platelet count in patients admitted with sepsis and septic shock is limited.
Tobias Schupp   +11 more
doaj   +1 more source

What can we learn from senescent platelets, their transcriptomes and proteomes? [PDF]

open access: yes, 2023
Research into the natural aging process of platelets has garnered much research interest in recent years, and there have long been associations drawn between the proportion of newly formed platelets in the circulation and the risk of thrombosis. However,
Vadgama, A   +7 more
core   +1 more source

Platelets and Anti-platelet Therapy

open access: yesJournal of Pharmacological Sciences, 2003
Platelets play a central role in the hemostatic process and consequently are similarly involved in the pathological counterpart, thrombosis. They adhere to various subendothelial proteins, exposed either by injury or disease, and subsequently become activated by the thrombogenic surface or locally produced agonists.
McNicol, Archibald, Israels, Sara J.
openaire   +4 more sources

Recent advances in understanding spleen tyrosine kinase (SYK) in human biology and disease, with a focus on fostamatinib

open access: yesPlatelets, 2023
Spleen tyrosine kinase (SYK) is an important regulatory molecule of signal transduction pathways involved in the pathogenesis of autoimmune diseases such as immune thrombocytopenia (ITP), and the SYK-signaling pathway has emerged as a potential target ...
Nichola Cooper   +5 more
doaj   +1 more source

Platelet index on admission as a predictor of bacteremia in acute cholangitis: a 7-year retrospective observational study

open access: yesPlatelets, 2022
Bacteremia frequently occurs in patients with acute cholangitis, which could increase the risk of mortality. This single-center retrospective observational study was conducted from July 2013 to July 2020 to evaluate the predictive value of platelet index
XiaoYing Chen   +3 more
doaj   +1 more source

Effects of exercise on platelet reactivity after myocardial infarction: a randomized clinical trial

open access: yesPlatelets, 2022
Exercise training (ET) can lower platelet reactivity in patients with cardiovascular risk factors. However, the effects of ET on platelet reactivity in higher-risk patients is unknown.
Talia Falcão Dalçóquio   +14 more
doaj   +1 more source

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