Results 11 to 20 of about 366,065 (267)

Gender-related differences in changes of estimated bleeding risk in patients on dual antiplatelet therapy: the RE-SCORE multicenter prospective registry

open access: yesPlatelets, 2022
The risk of bleeding as predicted by the PRECISE-DAPT score can vary over time after percutaneous coronary intervention (PCI). We sought to compare the predictive ability of the PRECISE-DAPT score calculated at baseline and reassessed during follow-up in
Francesco Pelliccia   +10 more
doaj   +1 more source

Diagnostic and prognostic role of platelets in patients with sepsis and septic shock

open access: yesPlatelets, 2023
Studies investigating the prognostic role of platelets commonly include critically ill patients, whereas data regarding the prognostic impact of platelet count in patients admitted with sepsis and septic shock is limited.
Tobias Schupp   +11 more
doaj   +1 more source

Platelet fibrinogen [PDF]

open access: yesJournal of Clinical Pathology, 1965
Platelet fibrinogen has been studied in normal, thrombasthenic, and hypofibrinogenaemic subjects. It has been differentiated into adsorbed (plasma) and extractable (intraplatelet) fractions. Isotopic studies suggest that exchange does not occur between intraplatelet and plasma fibrinogen and it appears possible that the intra-platelet fraction may be ...
P A, Castaldi, J, Caen
openaire   +2 more sources

Recent advances in understanding spleen tyrosine kinase (SYK) in human biology and disease, with a focus on fostamatinib

open access: yesPlatelets, 2023
Spleen tyrosine kinase (SYK) is an important regulatory molecule of signal transduction pathways involved in the pathogenesis of autoimmune diseases such as immune thrombocytopenia (ITP), and the SYK-signaling pathway has emerged as a potential target ...
Nichola Cooper   +5 more
doaj   +1 more source

Platelet index on admission as a predictor of bacteremia in acute cholangitis: a 7-year retrospective observational study

open access: yesPlatelets, 2022
Bacteremia frequently occurs in patients with acute cholangitis, which could increase the risk of mortality. This single-center retrospective observational study was conducted from July 2013 to July 2020 to evaluate the predictive value of platelet index
XiaoYing Chen   +3 more
doaj   +1 more source

Effects of exercise on platelet reactivity after myocardial infarction: a randomized clinical trial

open access: yesPlatelets, 2022
Exercise training (ET) can lower platelet reactivity in patients with cardiovascular risk factors. However, the effects of ET on platelet reactivity in higher-risk patients is unknown.
Talia Falcão Dalçóquio   +14 more
doaj   +1 more source

Roles of non-coding RNA in megakaryocytopoiesis and thrombopoiesis: new target therapies in ITP

open access: yesPlatelets, 2023
Noncoding RNAs (ncRNAs) are a group of RNA molecules that cannot encode proteins, and a better understanding of the complex interaction networks coordinated by ncRNAs will provide a theoretical basis for the development of therapeutics targeting the ...
Wuquan Li, Yan Lv, Yeying Sun
doaj   +1 more source

Apoptosis is one cause of thrombocytopenia in patients with high-altitude polycythemia

open access: yesPlatelets, 2023
High-altitude polycythemia (HAPC) can occur in individuals who are intolerant to high-altitude hypoxia. In patients with HAPC, erythrocytosis is often accompanied by a decrease in platelet count.
Zhuoya Wang   +7 more
doaj   +1 more source

Treatment inequity in antiplatelet therapy for ischaemic heart disease in patients with advanced chronic kidney disease: releasing the evidence vacuum

open access: yesPlatelets, 2023
Chronic kidney disease (CKD) is a global health problem and an independent risk factor for cardiovascular morbidity and mortality. Despite evidence-based therapies significantly improving cardiovascular mortality outcomes in the general population and ...
Frances L. Varian   +3 more
doaj   +1 more source

The CalDAG-GEFI/Rap1/αIIbβ3 axis minimally contributes to accelerated platelet clearance in mice with constitutive store-operated calcium entry

open access: yesPlatelets, 2023
Circulating platelets maintain low cytosolic Ca2+ concentrations. At sites of vascular injury, agonist-induced Ca2+ release from platelet intracellular stores triggers influx of extracellular Ca2+, a process known as store-operated Ca2+ entry (SOCE ...
Robert H. Lee   +3 more
doaj   +1 more source

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