Results 21 to 30 of about 432,603 (317)
Roles of non-coding RNA in megakaryocytopoiesis and thrombopoiesis: new target therapies in ITP
Platelets, 2023 Noncoding RNAs (ncRNAs) are a group of RNA molecules that cannot encode proteins, and a better understanding of the complex interaction networks coordinated by ncRNAs will provide a theoretical basis for the development of therapeutics targeting the ...
Wuquan Li, Yan Lv, Yeying Sun
doaj +1 more source
Apoptosis is one cause of thrombocytopenia in patients with high-altitude polycythemia
Platelets, 2023 High-altitude polycythemia (HAPC) can occur in individuals who are intolerant to high-altitude hypoxia. In patients with HAPC, erythrocytosis is often accompanied by a decrease in platelet count.
Zhuoya Wang +7 more
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Platelets, 2023 Chronic kidney disease (CKD) is a global health problem and an independent risk factor for cardiovascular morbidity and mortality. Despite evidence-based therapies significantly improving cardiovascular mortality outcomes in the general population and ...
Frances L. Varian +3 more
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Platelets, 2023 Circulating platelets maintain low cytosolic Ca2+ concentrations. At sites of vascular injury, agonist-induced Ca2+ release from platelet intracellular stores triggers influx of extracellular Ca2+, a process known as store-operated Ca2+ entry (SOCE ...
Robert H. Lee +3 more
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Platelets in Malarial Infection: Protective or Pathological?
, 2020 Platelets play an ambiguous role in a malarial infection. On the one hand, platelets have been implicated adversely in cerebral malaria. They stick to the cerebral endothelium and mediate the adhesion of infected erythrocytes, with the postulated outcome
Foote, Simon +2 more
core +1 more source
, 2023 Platelets are transfused to patients to prevent bleeding. Since both preparation and storage can impact the hemostatic functions of platelets, we studied platelet concentrates (PCs) with different initial composition in regard to platelet fragmentation ...
Dermot Kenny +35 more
core +1 more source
Evaluation of human platelet granules by structured illumination laser fluorescence microscopy
Platelets, 2023 Many roles of human platelets in health and disease are linked to their ability to transport and secrete a variety of small molecules and proteins carried in dense (δ-) and α-granules.
Fred G. Pluthero, Walter H. A. Kahr
doaj +1 more source
Normalization of qPCR in platelets – YWHAE a potential genericreference gene
, 2016 The mRNA of human platelets has been extensively studied and it is generally appreciated that platelets contain mRNA transcripts derived from the megakaryocytes, and they have the ability to translate it into proteins.
Svensson, Per-Arne, +15 more
core +1 more source
Developing human tissue engineered arterial constructs to simulate human in vivo thrombus formation
Platelets, 2023 Thrombus formation is highly dependent upon the physico-chemical environment in which it is triggered. Our ability to understand how thrombus formation is initiated, regulated, and resolved in the human body is dependent upon our ability to replicate the
Jacob Ranjbar +2 more
doaj +1 more source
Association of immature platelets with perioperative complications in neurosurgery
Platelets, 2023 Immature platelets are newly formed platelets with an increased prothrombotic potential. This study evaluates whether immature platelets are associated with relevant complications in neurosurgical patients.
Aida Anetsberger +10 more
doaj +1 more source