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Platelet transfusion refractoriness [PDF]
British Journal of Haematology, 2008 SummaryThe platelet, a fascinating anucleate cell, is critically important for haemostasis. Platelet transfusions have greatly reduced the incidence of major haemorrhagic complications associated with the management of haematological and oncological disorders. However, some patients fail to receive the full benefit of platelet transfusions because they
Eldad Hod
exaly +3 more sources
Mechanism and transfusion strategy of immunogenic platelet transfusion refractoriness
Zhongguo shuxue zazhi, 2022 Platelet transfusion is an irreplaceable method to treat patients with platelet reduction in Hematology Department and Oncology Department. However, immunogenic platelet transfusion refractoriness is a huge challenge to patients who require repeatedly ...
Juan SAI, Li TIAN
doaj +1 more source
Transfusion effect of 0.5-dose of apheresis platelet in pediatric patients
Zhongguo shuxue zazhi, 2023 Objective To investigate the transfusion effect of 0.5-dose of apheresis platelet in pediatric patients. Methods A total of 195 children who underwent 0.5-dose platelet transfusion from August 2021 to June 2022 were enrolled, and the platelet count ...
Lijuan QIU +3 more
doaj +1 more source
Asian Journal of Transfusion Science, 2021 Conventional platelet transfusion may not be adequate to deal with platelet transfusion refractoriness (PTR), and therefore human leukocyte antigen (HLA) or human platelet antigen (HPA) matched and platelet crossmatch compatible units are recommended ...
Gayathiri K Chellaiya +5 more
doaj +1 more source
The Lancet, 2007 Ever since platelet transfusions were shown to reduce mortality from haemorrhage in patients with acute leukaemia in the 1950s, the use of this therapy has steadily grown to become an essential part of the treatment of cancer, haematological malignancies, marrow failure, and haematopoietic stem cell transplantation.
Stroncek, David F., Rebulla, Paolo
openaire +3 more sources
Frontiers in Medicine, 2022 PurposeSepsis with thrombocytopenia is highly prevalent in critically ill intensive care unit (ICU) patients and is associated with adverse outcomes. Platelet transfusion is the primary treatment of choice. However, evidence for the beneficial effects of
Shuangjun He +4 more
doaj +1 more source
Critical Care, 2023 Background Response to prophylactic platelet transfusion is suspected to be inconsistent in critically ill patients questioning how to optimize transfusion practices.
Florian Reizine +19 more
doaj +1 more source
Efficacy of apheresis platelet transfusion in 310 patients with haematological diseases
Zhongguo shuxue zazhi, 2023 Objective To observe the effect of platelet transfusion in inpatients with haematological diseases, analyze the possible causes of platelet transfusion refractoriness (PTR), in order to further improve the efficacy of platelet transfusion.
Shisong YOU +5 more
doaj +1 more source
Zhongguo shuxue zazhi, 2023 Objective To study the platelet transfusion predictive models in tumor patients and evaluate its application effect. Methods A retrospective study was conducted on 944 tumor patients, including 533 males and 411 females who received platelet transfusion ...
Gang ZHAO +4 more
doaj +1 more source
Research progress of neonatal low-threshold platelet transfusion strategy
Zhongguo shuxue zazhi, 2023 Neonatal thrombocytopenia is one of the common hematological abnormalities in neonates, especially premature infants. Platelet transfusion is an effective method of treating neonatal thrombocytopenia, but its threshold selection and timing are ...
Chunfeng LIANG +4 more
doaj +1 more source