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Platelet transfusions [PDF]

The Lancet, 2007
Ever since platelet transfusions were shown to reduce mortality from haemorrhage in patients with acute leukaemia in the 1950s, the use of this therapy has steadily grown to become an essential part of the treatment of cancer, haematological malignancies, marrow failure, and haematopoietic stem cell transplantation.
David F, Stroncek, Paolo, Rebulla
openaire   +4 more sources

Randomized Trial of Platelet‐Transfusion Thresholds in Neonates

New England Journal of Medicine, 2019
BACKGROUND Platelet transfusions are commonly used to prevent bleeding in preterm infants with thrombocytopenia. Data are lacking to provide guidance regarding thresholds for prophylactic platelet transfusions in preterm neonates with severe ...
A. Curley, S. Stanworth, K. Willoughby, S. F. Fustolo-Gunnink, V. Venkatesh, C. Hudson, A. Deary, R. Hodge, V. Hopkins, Beatriz Lopez Santamaria, A. Mora, C. Llewelyn, A. D’Amore, R. Khan, W. Onland, E. Lopriore, Karin Fijnvandraat, H. New, P. Clarke, T. Watts   +19 more
semanticscholar   +3 more sources

Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral haemorrhage associated with antiplatelet therapy (PATCH): a randomised, open-label, phase 3 trial.

Lancet, The, 2016
M. I. Baharoglu, C. Cordonnier, R. Salman, K. de Gans, M. Koopman, A. Brand, C. B. Majoie, L. Beenen, H. Marquering, M. Vermeulen, P. Nederkoorn, R. J. de Haan, Yvo B. W. E. M. Roos   +12 more
semanticscholar   +3 more sources

Impact of platelet transfusion on outcomes in trauma patients

Critical Care, 2022
Background Trauma-induced coagulopathy includes thrombocytopenia and platelet dysfunction that impact patient outcome. Nevertheless, the role of platelet transfusion remains poorly defined.
S. Hamada, D. Garrigue, H. Nougué, A. Meyer, M. Boutonnet, E. Meaudre, A. Culver, E. Gaertner, G. Audibert, B. Vigué, J. Duranteau, A. Godier, Paer-Selim Gérard Tobias Thomas Anatole Olivier Marc Julien L Abback Audibert Gauss Geeraerts Harrois Langeron L, P. Abback, G. Audibert, T. Gauss, T. Geeraerts, A. Harrois, O. Langeron, M. Leone, J. Pottecher, L. Stecken, J. Hanouz   +22 more
semanticscholar   +1 more source

Platelet transfusion in adults: an update.

Transfusion Clinique et Biologique, 2022
Many patients worldwide receive platelet components (PCs) through the transfusion of diverse types of blood components. PC transfusions are essential for the treatment of central thrombocytopenia of diverse causes, and such treatment is beneficial in ...
O. Garraud, H. Hamzeh-Cognasse, E. Chalayer, A. Duchez, B. Tardy, P. Oriol, A. Haddad, D. Guyotat, F. Cognasse   +8 more
semanticscholar   +1 more source

Evaluation and management of platelet transfusion refractoriness

Blood Research, 2022
Platelet transfusion refractoriness (PTR), in which platelet counts do not increase after transfusion, occurs in many patients receiving platelet transfusions. PTR is a clinical condition that can harm patients.
Hee-Jeong Youk, Sang-Hyun Hwang, Heung-Bum Oh, D. Ko   +3 more
semanticscholar   +1 more source

Efficacy of apheresis platelet transfusion in 310 patients with haematological diseases

Zhongguo shuxue zazhi, 2023
Objective To observe the effect of platelet transfusion in inpatients with haematological diseases, analyze the possible causes of platelet transfusion refractoriness (PTR), in order to further improve the efficacy of platelet transfusion.
Shisong YOU, Liqi LU, Qun CAI, Xiaomei LI, Xiulan HUANG, Jingwei ZHANG   +5 more
doaj   +1 more source

Establishment and evaluation of predictive models of platelet transfusion effect in multi-center tumor patients

Zhongguo shuxue zazhi, 2023
Objective To study the platelet transfusion predictive models in tumor patients and evaluate its application effect. Methods A retrospective study was conducted on 944 tumor patients, including 533 males and 411 females who received platelet transfusion ...
Gang ZHAO, Fan GUO, Qing LI, Yihua XIE, Jun LI   +4 more
doaj   +1 more source

Implementation of a neonatal platelet transfusion guideline to reduce non-indicated transfusions using a quality improvement framework

Journal of Perinatology, 2021
Variation exists in neonatal platelet transfusion practices. Recent studies found potential harm in liberal platelet transfusion practices, supporting the use of lower transfusion thresholds.
Patricia E. Davenport, Jenny Chan Yuen, J. Brière, H. Feldman, M. Sola-Visner, Kristen T. Leeman   +5 more
semanticscholar   +1 more source

Prophylactic platelet transfusion response in critically ill patients: a prospective multicentre observational study

Critical Care, 2023
Background Response to prophylactic platelet transfusion is suspected to be inconsistent in critically ill patients questioning how to optimize transfusion practices.
Florian Reizine, Sarah Le Marec, Anthony Le Meur, Maëlys Consigny, Florian Berteau, Laetitia Bodenes, Marie Geslain, Zoe McQuilten, Catherine Le Niger, Julien Huntzinger, Philippe Seguin, Jean-Baptiste Thibert, David Simon, Jean Reignier, Pierre-Yves Egreteau, Jean-Marc Tadié, Olivier Huet, Pierre Asfar, Stephan Ehrmann, Cécile Aubron   +19 more
doaj   +1 more source