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Platelet Biochemistry and Morphology after Cryopreservation [PDF]

open access: yes, 2020
Platelet cryopreservation has been investigated for several decades as an alternative to room temperature storage of platelet concentrates. The use of dimethylsulfoxide as a cryoprotectant has improved platelet storage and cryopreserved concentrates can ...
Compernolle, Veerle   +2 more
core   +1 more source

Research progress of neonatal low-threshold platelet transfusion strategy

open access: yesZhongguo shuxue zazhi, 2023
Neonatal thrombocytopenia is one of the common hematological abnormalities in neonates, especially premature infants. Platelet transfusion is an effective method of treating neonatal thrombocytopenia, but its threshold selection and timing are ...
Chunfeng LIANG   +4 more
doaj   +1 more source

Effect of AB platelet secondary compatible transfusion on the efficacy of matched platelet transfusion

open access: yesZhongguo shuxue zazhi, 2023
Objective To retrospectively analyze the effect of AB platelet secondary compatible transfusion on the efficacy of matched platelet transfusion. Methods A total of 2 276 cases of platelet transfusion in our hospital were selected from November 2020 to ...
Yan HU   +6 more
doaj   +1 more source

Microfluidic flow chambers using reconstituted blood to model hemostasis and platelet transfusion in vitro [PDF]

open access: yes, 2016
Blood platelets prepared for transfusion gradually lose hemostatic function during storage. Platelet function can be investigated using a variety of (indirect) in vitro experiments, but none of these is as comprehensive as microfluidic flow chambers.
Compernolle, Veerle   +4 more
core   +2 more sources

Patch: platelet transfusion in cerebral haemorrhage: study protocol for a multicentre, randomised, controlled trial

open access: yesBMC Neurology, 2010
BackgroundPatients suffering from intracerebral haemorrhage have a poor prognosis, especially if they are using antiplatelet therapy. Currently, no effective acute treatment option for intracerebral haemorrhage exists.
K. de Gans   +7 more
semanticscholar   +1 more source

Platelets promote macrophage polarization toward pro-inflammatory phenotype and increase survival of septic mice [PDF]

open access: yes, 2019
We investigated the contribution of human platelets to macrophage effector properties in the presence of lipopolysaccharide (LPS), as well as the beneficial effects and time frame for platelet transfusion in septic animals.
Carestia, Agostina   +9 more
core   +1 more source

Leucoreduction of blood components. an effective way to increase blood safety? [PDF]

open access: yes, 2015
Over the past 30 years, it has been demonstrated that removal of white blood cells from blood components is effective in preventing some adverse reactions such as febrile non-haemolytic transfusion reactions, immunisation against human leucocyte antigens
Bianchi, Maria   +6 more
core   +1 more source

Intraoperative blood transfusions in highly alloimmunized patients undergoing orthotopic liver transplantation. [PDF]

open access: yes, 1989
Intraoperative blood requirements were analyzed in patients undergoing primary orthotopic liver transplantation and divided into two groups on the basis of panel reactive antibody of pretransplant serum measured by lymphocytotoxicity testing.
Duquesnoy, RJ   +5 more
core   +1 more source

Platelet Transfusion Practice and Related Outcomes in Pediatric Extracorporeal Membrane Oxygenation*

open access: yesPediatric Critical Care Medicine, 2020
Supplemental Digital Content is available in the text. Objective: To describe factors associated with platelet transfusion during pediatric extracorporeal membrane oxygenation and the relationships among platelet transfusion, complications, and mortality.
Katherine Cashen   +12 more
semanticscholar   +1 more source

Platelet transfusion refractoriness [PDF]

open access: yesBritish Journal of Haematology, 2008
SummaryThe platelet, a fascinating anucleate cell, is critically important for haemostasis. Platelet transfusions have greatly reduced the incidence of major haemorrhagic complications associated with the management of haematological and oncological disorders. However, some patients fail to receive the full benefit of platelet transfusions because they
Eldad, Hod, Joseph, Schwartz
openaire   +2 more sources

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