Platelet function tests: a comparative review [PDF]
Vascular Health and Risk Management, 2015 Rita Paniccia,1,2 Raffaella Priora,1,2 Agatina Alessandrello Liotta,2 Rosanna Abbate1,2 1Department of Experimental and Clinical Medicine, Thrombosis Center, University of Florence, Florence, Italy; 2Department of Heart and Vessels, Azienda Ospedaliero ...
Paniccia R +3 more
doaj +6 more sources
A Sticky Situation: Variable Agreement Between Platelet Function Tests Used to Assess Anti-platelet Therapy Response [PDF]
Frontiers in Cardiovascular Medicine, 2022 BackgroundPlatelet function testing to monitor antiplatelet therapy is important for reducing thromboembolic complications, yet variability across testing methods remains challenging.
Hirotomo Nakahara +8 more
doaj +2 more sources
Clopidogrel versus ticagrelor in the treatment of Chinese patients undergoing percutaneous coronary intervention: effects on platelet function assessed by platelet function tests and mean platelet volume [PDF]
Thrombosis Journal, 2021 Background Knowledge on the pharmacodynamic effects of antiplatelet drugs including clopidogrel and ticagrelor on Asian patients is scarce. We aim to evaluate the effects of the two drugs on platelet reactivity in the treatment of Chinese patients who ...
Yang Zhang +8 more
doaj +2 more sources
Research and Practice in Thrombosis and Haemostasis, 2019 Laboratory tests of platelet function are instrumental in studying platelet physiology and inherited or acquired platelet abnormalities. Light transmission aggregometry, developed in the early 1960s, is still considered the gold standard for the ...
Béatrice Hechler +3 more
doaj +2 more sources
Sensitivity of Viscoelastic Tests to Platelet Function [PDF]
Journal of Clinical Medicine, 2020 Viscoelastic tests provide a dynamic assessment of coagulation, by exploring the time to clot formation and the clot strength. Using specific activators or inhibitors, additional factors can be explored, like the fibrinogen contribution to clot strength.
Ekaterina Baryshnikova
exaly +3 more sources
Utility of preoperative in vitro platelet function tests for predicting bleeding risk in patients undergoing functional endoscopic sinus surgery [PDF]
Journal of Blood Medicine, 2016 A-Jin Lee, Sang-Gyung Kim Department of Laboratory Medicine, Catholic University of Daegu School of Medicine, Daegu, Republic of Korea Background: It is necessary to predict the bleeding risk in patients undergoing functional endoscopic sinus ...
Lee AJ, Kim S
doaj +2 more sources
Markers for platelet function testing by flow cytometry: where are we now? A clinical perspective [PDF]
Research and Practice in Thrombosis and HaemostasisFlow cytometry is transforming platelet function testing by offering high sensitivity, low sample requirements, and compatibility with thrombocytopenic and pediatric specimens.
Benjamin E.J. Spurgeon
doaj +2 more sources
Primary surgical bleeding and platelet function are unchanged in heartworm-infected dogs [PDF]
Frontiers in Veterinary ScienceIntroductionHeartworm-infected dogs may have changes in platelet function which can manifest as either perioperative bleeding or thrombosis, reflecting either a prothrombotic state from platelet hyperreactivity or hypocoagulability secondary to ...
Peyton A. Cole +5 more
doaj +2 more sources
Acquired platelet dysfunction induced by infection in an older patient: Severe hemorrhage despite normal platelet count [PDF]
SAGE Open Medical Case ReportsWe report a rare case of acquired, transient platelet dysfunction induced by infection in an older patient. An 84-year-old female with persistent pneumonia presented with severe mucocutaneous bleeding and anemia (nadir hemoglobin: 38 g/L) despite normal ...
Yuanyuan Jiang +6 more
doaj +2 more sources
Early Platelet Dysfunction in Sepsis: An ICU Pilot Study [PDF]
PathogensPlatelets are critical for hemostasis and play an active role in immune responses to infection. While thrombocytopenia in sepsis is associated with poor outcomes, platelet dysfunction remains less explored.
Maria Grazia Bocci +15 more
doaj +2 more sources