Results 1 to 10 of about 180,554 (264)
Diagnosis of Inherited Platelet Disorders on a Blood Smear [PDF]
Journal of Clinical Medicine, 2020 Inherited platelet disorders (IPDs) are rare diseases featured by low platelet count and defective platelet function. Patients have variable bleeding diathesis and sometimes additional features that can be congenital or acquired. Identification of an IPD is desirable to avoid misdiagnosis of immune thrombocytopenia and the use of improper treatments ...
Andreas Greinacher +2 more
exaly +3 more sources
Diagnosis of inherited platelet disorders on a blood smear: a tool to facilitate worldwide diagnosis of platelet disorders [PDF]
Journal of Thrombosis and Haemostasis, 2017 Essentials There are many hereditary platelet disorders (HPD) but diagnosing these is challenging. We provide a method to diagnose several HPDs using standard blood smears requiring < 100 µL blood. By this approach, the underlying cause of HPD was characterized in ~25-30% of referred individuals.
Andreas Greinacher, Alessandro Pecci
exaly +4 more sources
Blood platelet research in autism spectrum disorders: In search of biomarkers [PDF]
Research and Practice in Thrombosis and Haemostasis, 2019 Autism spectrum disorder (ASD) is a clinically heterogeneous neurodevelopmental disorder that is caused by gene-environment interactions. To improve its diagnosis and treatment, numerous efforts have been undertaken to identify reliable biomarkers for autism.
Manisha Padmakumar +2 more
exaly +4 more sources
Platelet-leukocyte interactions: immunoregulatory role and pathophysiological relevance
Медицинская иммунология, 2022 Blood platelets are the central players in thrombosis and blood coagulation. Moreover, they also exhibit immunoregulatory properties and bridge hemostasis and immunity.
O. V. Pavlov +3 more
doaj +1 more source
Dialysis-related thrombocytopenia: a case report
Brazilian Journal of Nephrology, 2021 Thrombocytopenia is frequently observed in hemodialysis patients, and its correct investigation and control remain a challenge. It is estimated that during the hemodialysis session there is a drop of up to 15% in the platelet count, with recovery after ...
Irene Faria Duayer +6 more
doaj +2 more sources
Platelet Activation in Human Immunodeficiency Virus Type-1 Patients Is Not Altered with Cocaine Abuse. [PDF]
PLoS ONE, 2015 Recent work has indicated that platelets, which are anucleate blood cells, significantly contribute to inflammatory disorders. Importantly, platelets also likely contribute to various inflammatory secondary disorders that are increasingly associated with
Michelle Kiebala +5 more
doaj +1 more source
Psychiatry and Behavioral Sciences, 2022 Aim: the primary aim of this study was to determine whether the neutrophil / lymphocyte ratio, mean platelet volume, monocyte/ lymphocyte ratio and distribution width of red blood cells are different in children with specific learning disorders compared ...
Cigdem Yektas +5 more
doaj +1 more source
The utility of flow cytometric platelet forward scatter as an alternative to mean platelet volume
Platelets, 2022 The use of mean platelet diameter (MPD) to classify inherited thrombocytopenia (IT) has been demonstrated in several studies. Alternatively, the mean platelet volume (MPV) may be used, but in macrothrombocytopenia this may not be available.
David Connor +12 more
doaj +1 more source
BMC Research Notes, 2021 Objective Hospital data are a useful resource for studying pregnancy complications, including bleeding-related conditions, however, the reliability of these data is unclear.
Heather J. Baldwin +5 more
doaj +1 more source
Лечащий Врач, 2023 The purpose of the work is the relevance of multilevel influence of deficiency of some nutrients on children's health. Nowadays, "unexplained" hemorrhagic syndrome is quite common in children. At the same time, standard methods of examination of patients
O. B. Gordeeva +4 more
doaj +1 more source