Platelets, 2022 Light transmission aggregometry (LTA) is the gold standard for the diagnosis of platelet function disorders (PFDs). The requirement of customized aggregometer, large blood volume, normal platelet count and processing within 4 hours of venipuncture for ...
Rutvi Gautam Dave +7 more
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Platelet interaction with bioactive lipids formed by mild oxidation of low-density lipoprotein [PDF]
, 2006 Oxidation of low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic mediators that play a crucial role in cardiovascular and inflammatory diseases.
Wolfgang Siess, Siess, Wolfgang
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Long-Term Outcome of Otherwise Healthy Individuals with Incidentally Discovered Borderline Thrombocytopenia. [PDF]
, 2006 BACKGROUND: The long-term outcome of individuals with mild degrees of thrombocytopenia is unknown. METHODS AND FINDINGS: In a prospective study conducted between August 1992 and December 2002, 260 apparently healthy individuals with incidentally ...
Sergio Amadori +17 more
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A novel likely pathogenic variant in the RUNX1 gene as the cause of congenital thrombocytopenia
Balkan Journal of Medical Genetics, 2023 Heterozygous pathogenic and likely pathogenic sequence variants in the RUNX1 (Runt-related Transcription Factor 1) gene are a common genetic cause of decreased platelet count and/or platelet dysfunction and an increased risk of developing myelodysplasia ...
Despotović M +6 more
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Tzu Chi Medical Journal, 2022 Platelets play an essential role in primary hemostasis through bleeding and thromboembolism. Thus, the diagnosis or evaluation of impaired hereditary, acquired, and drug-related platelet dysfunction has become imperative.
Chih-Lung Shen, Yi-Feng Wu
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Physico-Biochemical comparative study for Thyroid disorder patients in Ramadi city [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2015 The study aims at determining the impact of thyroid disorders in some blood and biochemical changes to try determine changes in some of the functions of the body as a result of these disorders, whether physiological or biochemical.
Muthana M. Awad, Abbas A. Hamdi
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FREQUENCY OF INHERITED PLATELE FUNCTION DISORDERS–ARMED FORCES INSTITUTE OF PATHOLOGY EXPERIENCE
Pakistan Armed Forces Medical Journal, 2020 Objective: To determine the frequency and clinical features of inherited platelet function disorders diagnosed at Armed Forces Institute of Pathology. Study Design: Cross sectional study.
Saira Irum +5 more
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Use of microfluidics to assess the platelet-based control of coagulation
Platelets, 2017 This paper provides an overview of the various types of microfluidic devices that are employed to study the complex processes of platelet activation and blood coagulation in whole blood under flow conditions. We elaborate on how these devices are used to
Magdolna Nagy +2 more
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Laboratory analyses for evaluation of platelet disorders and platelet concentrates [PDF]
, 2006 High quality of platelet analytics requires specialized knowledge and skills. It was applied to analyze platelet activation and aggregation responses in a prospective controlled study of patients with Finnish type of amyloidosis.
Javela, Kaija
core
Methylglyoxal induces platelet hyperaggregation and reduces thrombus stability by activating PKC and inhibiting PI3K/Akt pathway [PDF]
, 2013 Diabetes is characterized by a dysregulation of glucose homeostasis and platelets from patients with diabetes are known to be hyper-reactive and contribute to the accelerated development of vascular diseases.
Voahanginirina Randriamboavonjy +14 more
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