Results 11 to 20 of about 180,554 (264)
Variants in ETV6, which encodes a transcription repressor of the E26 transformation-specific family, have recently been reported to be responsible for inherited thrombocytopenia and hematologic malignancy. We sequenced the DNA from cases with unexplained
Marjorie Poggi +26 more
doaj +1 more source
Platelet aggregation impacts thrombin generation assessed by calibrated automated thrombography
A calibrated automated thrombogram (CAT) is performed usually with human platelet-free plasma (PFP) but may be more relevant with platelet-rich plasma (PRP). In this case, platelets are not stimulated by subendothelial molecules like collagen.
Mélusine Didelot +5 more
doaj +1 more source
Sticky Platelet Syndrome in Patients with Uninduced Venous Thrombosis
OBJECTIVE: Sticky platelet syndrome (SPS) is a common autosomal dominant inherited platelet disorder. SPS is characterized by platelet hyperreactivity and is associated with arterial and venous thrombosis.
Emre Tekgündüz +5 more
doaj +1 more source
Light transmission aggregometry (LTA) is the gold standard for the diagnosis of platelet function disorders (PFDs). The requirement of customized aggregometer, large blood volume, normal platelet count and processing within 4 hours of venipuncture for ...
Rutvi Gautam Dave +7 more
doaj +1 more source
A novel likely pathogenic variant in the RUNX1 gene as the cause of congenital thrombocytopenia
Heterozygous pathogenic and likely pathogenic sequence variants in the RUNX1 (Runt-related Transcription Factor 1) gene are a common genetic cause of decreased platelet count and/or platelet dysfunction and an increased risk of developing myelodysplasia ...
Despotović M +6 more
doaj +1 more source
Platelets play an essential role in primary hemostasis through bleeding and thromboembolism. Thus, the diagnosis or evaluation of impaired hereditary, acquired, and drug-related platelet dysfunction has become imperative.
Chih-Lung Shen, Yi-Feng Wu
doaj +1 more source
FREQUENCY OF INHERITED PLATELE FUNCTION DISORDERS–ARMED FORCES INSTITUTE OF PATHOLOGY EXPERIENCE
Objective: To determine the frequency and clinical features of inherited platelet function disorders diagnosed at Armed Forces Institute of Pathology. Study Design: Cross sectional study.
Saira Irum +5 more
doaj +4 more sources
Physico-Biochemical comparative study for Thyroid disorder patients in Ramadi city [PDF]
The study aims at determining the impact of thyroid disorders in some blood and biochemical changes to try determine changes in some of the functions of the body as a result of these disorders, whether physiological or biochemical.
Muthana M. Awad, Abbas A. Hamdi
doaj +1 more source
Use of microfluidics to assess the platelet-based control of coagulation
This paper provides an overview of the various types of microfluidic devices that are employed to study the complex processes of platelet activation and blood coagulation in whole blood under flow conditions. We elaborate on how these devices are used to
Magdolna Nagy +2 more
doaj +1 more source
Resolving the missing link between single platelet force and clot contractile force
Summary: Blood clot contraction plays an important role in wound healing and hemostasis. Although clot contraction is known to be driven by platelets, how single platelet forces relate to the forces generated by macroscopic clots remains largely unknown.
Yueyi Sun +4 more
doaj +1 more source

