Results 1 to 10 of about 5,594 (244)
In vitro flow assays utilizing microfluidic devices are often used to study human platelets as an alternative to the costly animal models of hemostasis and thrombosis that may not accurately represent human platelet behavior in vivo.
Alison Leigh Banka +1 more
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Atherosclerosis is the major cause of cardiovascular disease that is characterized by plaque formation in the blood vessel wall. Atherosclerotic plaques represent sites of chronic inflammation with diverse cell content that is shifted toward the ...
Daria M. Potashnikova +9 more
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Validated model of platelet slip at stenosis and device surfaces
Platelets are central to thrombosis. However, it is unknown whether platelets slip at vascular or device surfaces. The presence of platelet slip at a surface would interrupt physical contact between the platelet and that surface, and therefore diminish ...
Scott J. Denardo +8 more
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Coagulopathy and platelet abnormalities in patients with inflammatory bowel disease [PDF]
Inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, is associated with a hypercoagulable state that increases thromboembolic complication risk.
Dae Sung Kim, Won Moon
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This study examines the adhesive properties and cytotoxicity of polyelectrolyte nanofilms from polyethyleneimine (PEI), polyallylamine hydrochloride (PAH) and sodium polystyrene sulfonate (PSS) on human bone marrow mesenchymal stromal cells (h-MSCs) and ...
Lyudmila M. Mezhevikina +5 more
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Maternal neutrophils cells are players in gestational tolerance and fetus delivery. Nonetheless, their actions in each phase of the pregnancy are unknown.
Cristina Bichels Hebeda +7 more
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Leukocyte-platelet adhesion during hypoxia, tissue damage, activation of inflammation and coagulation is associated with the expression of ICAM-1 membrane molecules and integrins by blood and tissue cells.
I. D. Magamedov +15 more
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The influence of bevacizumab on platelet function
Systemic treatment with bevacizumab is associated with increased rates of arterial and venous thromboembolism and haemorrhage. In order to investigate the pathophysiological mechanism involved, platelet adhesive and aggregatory functions were tested
M Fehr +5 more
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Chemokines, molecular drivers of thromboinflammation and immunothrombosis
Blood clotting is a finely regulated process that is essential for hemostasis. However, when dysregulated or spontaneous, it promotes thrombotic disorders.
Julian Leberzammer +4 more
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Cardiovascular disease (CVD) is a major comorbidity in chronic obstructive pulmonary disease (COPD). Although the mechanism of its development remains largely unknown, it appears to be associated with cigarette consumption and reduced lung function ...
Patrice Marques +13 more
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