Liquoid and platelet aggregation
Abstract Liquoid, a synthetic acid polymer (sodium polyanethol sulphonate) can induce aggregation of human platelet rich plasma at concentrations ranging from 50 μg to 100 ug. Lower or higher concentrations are less effective. The aggregation of platelets which requires Ca++ is preceded by a lag phase of 30 to 60 seconds.
IATRIDIS, SG +4 more
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PLATELET PHAGOCYTOSIS AND AGGREGATION [PDF]
The addition of latex particles to native (no anticoagulant) or citrated human platelet-rich plasma (PRP), or to a once-washed platelet suspension causes platelet aggregation. This aggregation is associated with phagocytosis of the latex particles by the platelets and appears to be due to release of adenosine diphosphate (ADP) from the platelets ...
H Z, Movat +3 more
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Quercetin inhibits collagen-stimulated platelet activation through inhibition of multiple components of the glycoprotein VI signaling pathway [PDF]
Background: The regulation of platelet function by pharmacological agents that modulate platelet signaling haspharmacolo proven a successful approach to the prevention of thrombosis.
Cicmil, M +23 more
core +1 more source
Effect of 3-Day Storage and Temperature on ADP-induced Platelet Aggregation
Objective: To observe platelet functions during the 3 days of platelet storage and to evaluate the effect of storage temperature towards platelet aggregation response.
Nanda Ayu Puspita, Suryawati
doaj +1 more source
Role of platelet aggregation in metastatic breast cancer patients
Background and Aims: Breast cancer is the most common female cancer in the world. Although early detection and systematic adjuvant therapy has improved survival, distant metastasis remains the leading cause of breast related mortality.
Tanisha Singla +4 more
doaj +1 more source
Platelet interaction with bioactive lipids formed by mild oxidation of low-density lipoprotein [PDF]
Oxidation of low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic mediators that play a crucial role in cardiovascular and inflammatory diseases.
Wolfgang Siess, Siess, Wolfgang
core +1 more source
Garlic inhibitory effect on platelet activity induced by different agonists
Platelets are essential elements of human blood. In addition to their normal role, platelets are involved in causing myocardial infarction, stroke and other thrombotic disorders.
Roxana Elizabeth González +3 more
doaj +1 more source
Methylglyoxal induces platelet hyperaggregation and reduces thrombus stability by activating PKC and inhibiting PI3K/Akt pathway [PDF]
Diabetes is characterized by a dysregulation of glucose homeostasis and platelets from patients with diabetes are known to be hyper-reactive and contribute to the accelerated development of vascular diseases.
Voahanginirina Randriamboavonjy +14 more
core +1 more source
Shear‐dependent platelet aggregation size [PDF]
Nonsurgical bleeding is the most frequent complication of left ventricular assist device (LVAD) support. Supraphysiologic shear rates generated in LVAD causes impaired platelet aggregation, which increases the risk of bleeding.
Michael J. Simmonds +23 more
core +1 more source
Polyamines and platelet aggregation
Abstract High blood concentrations of the naturally occurring polyamines have been reported in leukemia, psoriasis, cystic fibrosis and polycythemia rubra vera. Spermidine and spermine inhibit in vitro plate-let aggregation of platelet rich plasma preparations in which ADP and Ristocetin are the agglutinating agents.
Division of Genetics, Endocrinology and Metabolism Departments of Pediatrics, Biochemistry and Neuroscience University of Florida, Gainesville-Sunland Research Laboratory Gainesville, Florida 32610, U.S.A. ( host institution ) +4 more
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