An investigation of the antiplatelet effects of succinobucol (AGI-1067) [PDF]
Platelets, 2017 Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects. Given the importance of oxidant stress in modulating platelet–platelet and platelet–vessel wall interactions, the aim of this study was to establish if antioxidant ...
Stephanie A. Houston +3 more
doaj +2 more sources
Evaluation of Anti-Platelet Aggregation Effect of Some Allium Species [PDF]
, 2015 Epidemiologic studies show that the cardiovascular diseases are associated with multiple factors such as raised serum total cholesterol, increased LDL, increased platelet aggregation, hypertension and smoking.
Amidi, Salimeh. +3 more
core +1 more source
A review of natural compounds to regulate platelet aggregation: molecular mechanism and research advance [PDF]
Frontiers in PharmacologyPlatelets are a class of blood cells exfoliated from bone marrow megakaryocytes and important participants in the blood. Aggregation is a prominent part of the platelets involved in the hemostasis process, regulated by multiple signaling pathways ...
Yi Hou +9 more
doaj +2 more sources
Macrostachyols A-D, oligostilbenes from Gnetum macrostachyum inhibited in vitro human platelet aggregation [PDF]
Journal of HerbMed Pharmacology, 2021 Introduction: Gnetum macrostachyum is a known Thai medicinal plant as a source of bioactive oligostilbenes, which possess platelet inhibitory activities.
Serm Surapinit, Nuttakorn Baisaeng
doaj +1 more source
Ex vivo STUDY OF THE ACTION OF INTEGRIN RECEPTORS ANTAGONIST FROM ECHIS MULTISQUAMATIS SNAKE VENOM ON PLATELETS OF PREGNANT WOMEN WITH COMPICATIONS DURING GESTATION [PDF]
Biotechnologia Acta, 2023 Aim. In our work, we studied platelet aggregation in blood plasma of pregnant women and estimated the possibility of ex vivo normalization of aggregation rate using a polypeptide from the Echis multisquamatus snake venom.
O. M. PLATONOV, I. V. US
doaj +1 more source
The Ratio of ADP- to TRAP-Induced Platelet Aggregation Quantifies P2Y12-Dependent Platelet Inhibition Independently of the Platelet Count. [PDF]
PLoS ONE, 2016 This study aimed to assess the association of clinical factors with P2Y12-dependent platelet inhibition as monitored by the ratio of ADP- to TRAP-induced platelet aggregation and conventional ADP-induced aggregation, respectively.Controversial findings ...
Christoph B Olivier +8 more
doaj +1 more source
Platelet aggregation pathway [PDF]
Pharmacogenetics and Genomics, 2011 Platelet activation and coagulation normally do not occur in an intact blood vessel. After blood vessel wall injury, platelet plug formation is initiated by the adherence of the platelets to subendothelial collagen [1,2]. In high shear arterial blood, platelets are first slowed down from their blood flow velocity by interacting with the collagen-bound ...
Katrin, Sangkuhl +3 more
openaire +2 more sources
Majalah Kedokteran Bandung, 2023 One of the causes of cerebral venous sinus thrombosis (CVST) is platelet hyperactivity. Adhesion and secretion are the beginning of platelet activation, which is indicated by a change in the Platelet-selectin (P-selectin) level.
Rahmawati Nurmin +4 more
doaj +1 more source
Journal of Pharmacological Sciences, 2022 Quinonoid dihydropteridine reductase (QDPR) regenerates tetrahydrobiopterin (BH4), which is an essential cofactor for catecholamine and serotonin (5-hydroxytryptamine, 5-HT) biosynthesis.
Yui Suganuma +6 more
doaj +1 more source
Optimized tool for evaluation of platelet function measured by impedance aggregometry
Platelets, 2021 Platelet aggregation measured by impedance aggregometry is highly dependent on platelet count. We previously developed a tool to interpret impedance aggregometry based on the strong linear correlation between platelet counts and platelet aggregation at ...
Anna Schultz-Lebahn +3 more
doaj +1 more source