Results 31 to 40 of about 1,637,470 (286)

Methylglyoxal induces platelet hyperaggregation and reduces thrombus stability by activating PKC and inhibiting PI3K/Akt pathway [PDF]

, 2013
Diabetes is characterized by a dysregulation of glucose homeostasis and platelets from patients with diabetes are known to be hyper-reactive and contribute to the accelerated development of vascular diseases.
Voahanginirina Randriamboavonjy, Ingrid Fleming, Amro Elgheznawy, Randriamboavonjy, Voahanginirina, Fleming, Ingrid, Amro Elgheznawy (458464), Karin Hadas, Hadas, Karin, Karin Hadas (458462), Alexander Mann (262817), Elgheznawy, Amro, Mann, Alexander, Ingrid Fleming (132865), Alexander Mann, Voahanginirina Randriamboavonjy (458463)   +14 more
core   +1 more source

Platelet aggregation in healthy women during normal pregnancy - a longitudinal study

Platelets, 2019
Increased platelet activation is involved in obstetric complications such as preeclampsia and intrauterine growth retardation. It is of interest to study platelet aggregation during pregnancy, since increased aggregation theoretically could be a ...
Lennart Rune Fredrik Blomqvist, Annika Margareta Strandell, Fariba Baghaei, Margareta Sofia Elisabet Hellgren   +3 more
doaj   +1 more source

Targeted deep sequencing of the PEAR1 locus for platelet aggregation in European and African American families

Platelets, 2019
Coronary artery disease (CAD) remains a major cause of mortality and morbidity worldwide. The aggregation of activated platelets on a ruptured atherosclerotic plaque is a critical step in most acute cardiovascular events like myocardial infarction ...
Ali R Keramati, Lisa R Yanek, Kruthika Iyer, Margaret A Taub, Ingo Ruczinski, Diane M Becker, Lewis C Becker, Nauder Faraday, Rasika A Mathias   +8 more
doaj   +1 more source

No impact of polymorphism in the phosphodiesterase 5A gene in Cavalier King Charles Spaniels on pimobendan‐induced inhibition of platelet aggregation response

Journal of Veterinary Internal Medicine, 2023
Background A variant in the canine phosphodiesterase (PDE) 5A gene (PDE5A:E90K) is associated with decreased concentrations of circulating cyclic guanosine monophosphate (cGMP) and response to PDE5 inhibitor treatment.
Maria J. Reimann, Daniel N. Faisst, Mads Knold, Kathryn M. Meurs, Joshua A. Stern, Signe E. Cremer, Jacob E. Møller, Ingrid Ljungvall, Jens Häggström, Lisbeth H. Olsen   +9 more
doaj   +1 more source

Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer

Nature Medicine, 2019
Non-alcoholic fatty liver disease ranges from steatosis to non-alcoholic steatohepatitis (NASH), potentially progressing to cirrhosis and hepatocellular carcinoma (HCC). Here, we show that platelet number, platelet activation and platelet aggregation are
Mohsen Malehmir, D. Pfister, S. Gallage, M. Szydlowska, Donato Inverso, E. Kotsiliti, Valentina Leone, M. Peiseler, B. Surewaard, D. Rath, Adnan Ali, M. Wolf, Hannah K. Drescher, M. E. Healy, D. Dauch, D. Kroy, O. Krenkel, M. Kohlhepp, Thomas Engleitner, Alexander Olkus, T. Sijmonsma, J. Volz, C. Deppermann, David Stegner, Patrick M. Helbling, C. Nombela-Arrieta, Anahita Rafiei, Martina Hinterleitner, Marcel Rall, Florian Baku, O. Borst, C. Wilson, J. Leslie, Tracy O'Connor, C. Weston, Abhishek Chauhan, D. Adams, L. Sheriff, Ana Teijeiro, M. Prinz, Ruzhica Bogeska, Natasha Anstee, M. Bongers, M. Notohamiprodjo, T. Geisler, D. Withers, J. Ware, D. Mann, H. Augustin, A. Vegiopoulos, M. Milsom, A. J. Rose, P. Lalor, J. Llovet, R. Pinyol, F. Tacke, R. Rad, M. Matter, N. Djouder, P. Kubes, P. Knolle, K. Unger, L. Zender, B. Nieswandt, M. Gawaz, A. Weber, Mathias Heikenwalder   +66 more
semanticscholar   +1 more source

Camel platelet aggregation responses and the antiplatelet effect of camel urine: comparison between black and white camels

Heliyon, 2020
Human black and white-skinned races exhibited differences in platelet aggregation. However, no similar differences were described on white and black camels.
Abeer Khalid Al-Ghumlas
doaj   +1 more source

Analysis of kinetics of light scattering by cell suspection during aggregation: mathematical modeling of platelet disaggregation

Вісник Харківського національногоуніверситету імені В.Н. Каразіна. Серія: Радіофізика та електроніка, 2021
Background. Molecular mechanisms of platelet aggregation are actively studied by methods of molecular cell biology, biochemistry, applied physics, but the problem of modeling the dynamics of this process remains open.
O. V. Pertsov, V. P. Berest
doaj   +1 more source

Effects of electronic cigarette flavorants on human platelet aggregation ex vivo

Toxicology Reports, 2022
Because little is known about the effects of individual flavorants in electronic cigarette (e-cig) fluids on human platelet aggregation, we tested for the direct effects of 15 common e-cig flavorants on adenosine diphosphate (ADP)-induced human platelet ...
Andre Richardson, Tatiana Krivokhizhina, Pawel Lorkiewicz, Stanley D’Souza, Aruni Bhatnagar, Sanjay Srivastava, Daniel J. Conklin   +6 more
doaj   +1 more source

Augmentation by resveratrol of the inhibitory effect of ethanol on platelet aggregation

Platelets, 2023
Ethanol and resveratrol have been shown to inhibit platelet aggregation. The aim of this study was to determine whether resveratrol has an additional effect on ethanol-induced inhibition of platelet aggregation.
Kazumi Ekawa, Mikio Marumo, Ichiro Wakabayashi   +2 more
doaj   +1 more source

Mucor circinelloides induces platelet aggregation through integrin αIIbβ3 and FcγRIIA

Platelets, 2019
Thrombosis is a hallmark of the fatal fungal infection mucormycosis. Yet, the platelet activation pathway in response to mucormycetes is unknown. In this study we determined the platelet aggregation potential of Mucor circinelloides (M.
Harlene Ghuman, Alicia Shepherd-Roberts, Stephanie Watson, Malou Zuidscherwoude, Steve P. Watson, Kerstin Voelz   +5 more
doaj   +1 more source