Influence of dietary linoleic acid intake with different fat intakes on arachidonic acid concentrations in plasma and platelet lipids and eicosanoid biosynthesis in female volunteers [PDF]
, 2003 Background/Aim: N-6 fatty acids are considered to promote diseases prevalent in industrialized countries and characterized by an increased eicosanoid biosynthesis from arachidonic acid (AA).
Zöllner, N., Adam, Olaf, Wolfram, G.
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The in vitro effect of antirheumatic drugs on platelet function
Platelets, 2020 Several antirheumatic drugs lower the cardiovascular risk among rheumatoid arthritis patients. It is, however, unknown whether inhibition of platelet function contributes to this risk reduction.
Camilla Brødsgaard Nielsen +4 more
doaj +1 more source
Prognostic Value of Platelet Aggregation Function in Patients with laryngeal Carcinoma
, 2023 Minghua Li,1,* Jiawei Gui,1,* Hao Wang,2 Jun An,3 Ruoqing Wu,1 Xiaotong Liu,1 Bo Wu,1 Hui Xiao1 1Department of Otolaryngology-Head and Neck Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150081, People’s Republic of
Liu X +7 more
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Reduced platelet activation and platelet aggregation in patients with alcoholic liver cirrhosis
Platelets, 2018 Results from previous studies regarding platelet function in liver cirrhosis are discordant. The aim was to investigate platelet activation and platelet aggregation in patients with alcoholic liver cirrhosis.
Pernille Just Vinholt +6 more
doaj +1 more source
Platelet Activation and Aggregation Induced by Streptococcus bovis/Streptococcus equinus Complex
Microbiology Spectrum, 2022 Streptococcus bovis/Streptococcus equinus complex (SBSEC) is a common cause of infective endocarditis (IE). For IE-pathogens, the capacity to activate and aggregate platelets is believed to be an important virulence mechanism.
Gustav Pernow +4 more
doaj +1 more source
Efeito inibitório duradouro do óxido nítrico sobre a agregação plaquetária [PDF]
, 2012 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em FarmacologiaA agregação plaquetária ocorre fisiologicamente para ocluir lesões em vasos ou em condições anormais como na ...
Gonçalves, Muryel de Carvalho
core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Effect of Oral Anti-platelet Regimens on Platelet Aggregation using Chronolog Light Transmittance Aggregometry in Coronary Heart Disease Patients: An Observational Study [PDF]
Journal of Clinical and Diagnostic Research, 2013 Introduction: Coronary heart disease is one of the most common cardiac health problem in India. Anti-platelet therapy is the cornerstone in the management of coronary heart disease.
Kishan P.V. +4 more
doaj +1 more source