Results 21 to 30 of about 142,225 (311)

Aggregation of platelets by collagen [PDF]

Journal of Clinical Investigation, 1968
In studying some of the properties of collagen responsible for the ability to aggregate platelets it was found that thermal treatment at pH 2.5 of acid-soluble human collagen resulted in a sharp reduction in relative viscosity and platelet aggregating activity at about 35 degrees C.
G D, Wilner, H L, Nossel, E C, LeRoy
openaire   +2 more sources

Dose-dependent effects of anthocyanin supplementation on platelet function in subjects with dyslipidemia: A randomized clinical trial

EBioMedicine, 2021
Background: Dyslipidemia induces platelet hyperactivation and hyper-aggregation, which are linked to thrombosis. Anthocyanins could inhibit platelet function in vitro and in mice fed high-fat diets with their effects on platelet function in subjects with
Zezhong Tian, Kongyao Li, Die Fan, Yimin Zhao, Xiaoli Gao, Xilin Ma, Lin Xu, Yilin Shi, Fuli Ya, Jinchao Zou, Ping Wang, Yuheng Mao, Wenhua Ling, Yan Yang   +13 more
doaj   +1 more source

Platelet aggregation pathway [PDF]

Pharmacogenetics and Genomics, 2011
Platelet activation and coagulation normally do not occur in an intact blood vessel. After blood vessel wall injury, platelet plug formation is initiated by the adherence of the platelets to subendothelial collagen [1,2]. In high shear arterial blood, platelets are first slowed down from their blood flow velocity by interacting with the collagen-bound ...
Katrin, Sangkuhl, Alan R, Shuldiner, Teri E, Klein, Russ B, Altman   +3 more
openaire   +2 more sources

Anti-platelet therapy: ADP receptor antagonists. [PDF]

, 2011
The P2Y(12) receptor on platelets with which ADP interacts has an important role in promoting platelet function and thereby platelet involvement in both haemostasis and thrombosis.
Heptinstall, S, Wijeyeratne, YD, Stan Heptinstall, Yanushi Dullewe Wijeyeratne   +3 more
core   +1 more source

The effect of butanolides from Cinnamomum tenuifolium on platelet aggregation [PDF]

, 2014
This study investigated the effects of isotenuifolide and tenuifolide B from the stems of Cinnamomum tenuifolium on adenosine diphosphate (ADP)-induced human platelet aggregation. Treatment of human platelet-rich plasma with isotenuifolide (1 and 2 μg/μL)
陳中一
core   +4 more sources

Thrombopoietin and platelet aggregation in patients with stable coronary artery disease

Platelets, 2017
Thrombopoietin (TPO) may facilitate platelet activation and aggregation. However, data on the impact of TPO on platelet aggregation in patients with stable coronary artery disease (CAD) are scarce.
Sanne Bøjet Larsen, Erik Lerkevang Grove, Søs Neergaard-Petersen, Morten Würtz, Anne-Mette Hvas, Steen Dalby Kristensen   +5 more
doaj   +1 more source

Platelet aggregation and quality control of platelet concentrates produced in the Amazon Blood Bank

Revista Brasileira de Hematologia e Hemoterapia, 2011
BACKGROUND: The study of platelet aggregation is essential to assess in vitro platelet function by different platelet activation pathways. OBJECTIVE: To assess aggregation and biochemical parameters of random platelet concentrates produced at the ...
Maria José Dantas Coêlho, Taysa de Castro Monteiro, Felicien Gonçalves Vasquez, Kátia Luz Torres Silva, Kleber Sandro Brasil dos Santos, Viviana Maria Araújo de Oliveira, Francimary de Oliveira Cavalcante   +6 more
doaj   +1 more source

Genetic determinants of on-aspirin platelet reactivity: focus on the influence of PEAR1.

PLoS ONE, 2014
BackgroundPlatelet aggregation during aspirin treatment displays considerable inter-individual variability. A genetic etiology likely exists, but it remains unclear to what extent genetic polymorphisms determine platelet aggregation in aspirin-treated ...
Morten Würtz, Peter H Nissen, Erik Lerkevang Grove, Steen Dalby Kristensen, Anne-Mette Hvas   +4 more
doaj   +1 more source

Platelet aggregation in healthy women during normal pregnancy - a longitudinal study

Platelets, 2019
Increased platelet activation is involved in obstetric complications such as preeclampsia and intrauterine growth retardation. It is of interest to study platelet aggregation during pregnancy, since increased aggregation theoretically could be a ...
Lennart Rune Fredrik Blomqvist, Annika Margareta Strandell, Fariba Baghaei, Margareta Sofia Elisabet Hellgren   +3 more
doaj   +1 more source

Targeted deep sequencing of the PEAR1 locus for platelet aggregation in European and African American families

Platelets, 2019
Coronary artery disease (CAD) remains a major cause of mortality and morbidity worldwide. The aggregation of activated platelets on a ruptured atherosclerotic plaque is a critical step in most acute cardiovascular events like myocardial infarction ...
Ali R Keramati, Lisa R Yanek, Kruthika Iyer, Margaret A Taub, Ingo Ruczinski, Diane M Becker, Lewis C Becker, Nauder Faraday, Rasika A Mathias   +8 more
doaj   +1 more source