Results 231 to 240 of about 447,619 (420)

Higher rate of microscopic hematuria in elderly patients who take regular doses of aspirin: Result from AHAP Study

open access: yesCaspian Journal of Internal Medicine, 2016
Background: Aspirin is the most widely used drug in medicine for cardiovascular and as recently for its role in cancer prevention. Although the risk of bleeding events increased following regular use of aspirin, little is known about the association of ...
Emadouddin Moudi   +2 more
doaj  

In Vitro and In Vivo Assessment of Platelet Function in Healthy Dogs during Low-Dose Aspirin Therapy [PDF]

open access: yes, 2014
Low-dose aspirin therapy in dogs inconsistently inhibits platelet function, termed ‘aspirin resistance’. There are no established diagnostic tests that can predict aspirin resistance in dogs prior to therapy.
Haines, Jillian Marie
core   +1 more source

The Type III Secretion System (T3SS) of Escherichia Coli Promotes Atherosclerosis in Type 2 Diabetes Mellitus

open access: yesAdvanced Science, EarlyView.
Large‐scale studies indicate a strong relationship between the gut microbiome, type 2 diabetes mellitus (T2DM), and atherosclerotic cardiovascular disease (ASCVD). Here, a higher abundance of the type III secretion system (T3SS) virulence factors of Enterobacteriaceae/Escherichia‐Shigella in patients with T2DM‐related‐ASCVD, which correlates with their
Yao‐Yuan Zhang   +15 more
wiley   +1 more source

Machine Learning‐Enabled Drug‐Induced Toxicity Prediction

open access: yesAdvanced Science, EarlyView.
Unexpected toxicity accounts for 30% of drug development failures. This review highlights ML innovations in predicting drug‐induced toxicity, emphasizing comparative analyses, interpretable algorithms, and multi‐source data integration. It categorizes toxicity types, summarizes ML models, and organizes key databases, offering strategies to address ...
Changsen Bai   +5 more
wiley   +1 more source

Polarized Color Filters Using Colloidal Quantum Rod Nanocrystals for Advanced High‐Performance Displays

open access: yesAdvanced Science, EarlyView.
This groundbreaking research has advanced the utilization of quantum rods (QRs) for the emission of linearly polarized light, resulting in exceptional color saturation and enhanced display efficiency. The developed filter demonstrates a polarization degree of up to 0.67 and an impressive ambient contrast ratio (ACR) of 263:1, setting the stage for ...
Jianxin Song   +12 more
wiley   +1 more source

Reshape the Fates of Treg and CD8+T Cells Through IL‐2Rα by Synergizing Divergent Receptor‐Biased IL‐2 PEGylates

open access: yesAdvanced Science, EarlyView.
This study presents receptor‐biased IL‐2 PEGylates that selectively modulate IL‐2 receptor subunit interactions to enhance CD8⁺ T cell antitumor activity while curbing Treg activation and endothelial toxicity. The combined not‐α and not‐β variants balance immune stimulation and prevent T cell exhaustion, offering a novel, fine‐tuned approach for ...
Jiaqi Sun   +23 more
wiley   +1 more source

Aspirin use correlates with survival in women with clear cell ovarian cancer

open access: yesGynecologic Oncology Reports, 2018
Data from colon, breast and prostate cancers suggest that aspirin users have reduced mortality. While the direct mechanism remains uncertain, aspirin can suppress the COX-dependent and independent pathways involved in tumor progression.
Alyssa M. Wield   +5 more
doaj  

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