Results 191 to 200 of about 88,625 (333)
Mechanism of Lenvatinib Resistance via Exosomal miRNA‐132/Nrf2 Axis in Hepatocellular Carcinoma
Annals of Gastroenterological Surgery, EarlyView.Exosomal miRNA‐132 from LVT‐res HCC cells activated Nrf2 expression through the PTEN/GSK3β pathway in recipient cells. This cascade could induce drug resistance in non‐resistant HCC cells in the TME. ABSTRACT Introduction Lenvatinib is a multiple receptor tyrosine kinase inhibitor and a first‐line targeted therapy for hepatocellular carcinoma (HCC ...
Chie Takasu +7 more
wiley +1 more source
High Frequency of Aspirin Resistance in Patients with Acute Coronary Syndrome
, 2005 Gültekin Hobikoğlu +6 more
openalex +2 more sources
Assessment of aspirin resistance varies on a temporal basis in patients with ischaemic heart disease [PDF]
, 2008 Alison Muir +3 more
openalex +1 more source
Annals of Gastroenterological Surgery, EarlyView.The key to unlocking ICI benefit in pMMR/MSS LARC is to convert “cold” tumors into “hot” ones through lymphocyte‐sparing SCRT and judicious chemotherapy, creating a milieu in which ICIs can act effectively. ABSTRACT The management of locally advanced rectal cancer (LARC) has evolved with the adoption of total neoadjuvant therapy (TNT), integrated ...
Yoshinori Kagawa +5 more
wiley +1 more source
Perioperative management of aspirin resistance after off‐pump coronary artery bypass grafting: possible role for aprotinin [PDF]
, 2008 Robert Poston +9 more
openalex +1 more source
Intelligent Theranostic Systems Enabled by Aggregation‐Induced Emission in Precision Medicine
Aggregate, EarlyView.Aggregation‐induced emission (AIE) luminogens are driving a new generation of intelligent theranostic systems that integrate high‐fidelity imaging and multifunctional therapy. This review highlights how AIEgens, through restriction of intramolecular motion (RIM), enable deep‐tissue NIR‐II imaging, ultrasensitive biosensing, CRISPR‐assisted gene ...
Qinqin Huang +7 more
wiley +1 more source
Prevalence of Aspirin Resistance in Patients with Transcatheter Pulmonary Valve Replacement. [PDF]
Catheter Cardiovasc IntervSigman A +4 more
europepmc +1 more source
Toward efficient quantum computation of molecular ground‐state energies
AIChE Journal, EarlyView.Abstract Variational quantum eigensolvers (VQEs) represent a promising approach to computing molecular ground states and energies on modern quantum computers. These approaches use a classical computer to optimize the parameters of a trial wave function, while the quantum computer simulates the energy by preparing and measuring a set of bitstring ...
Farshud Sorourifar +8 more
wiley +1 more source