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Case Report: The effect of asplenia on the response to influenza vaccination and passive transfer of immunity in an adult female pig [PDF]

Frontiers in Immunology
Asplenia is an important cause of morbidity and mortality in humans. However, there are only very rare examples of this condition reported in domesticated species. Here we present a case of asplenia, diagnosed at necropsy, in a crossbred adult female pig
Michael C. Rahe, John J. Byrne, Danielle Meritet, Erika Gruber, Stephanie N. Langel, Elisa Crisci   +5 more
doaj   +2 more sources

Case Report: Rethinking pulmonary arterial hypertension: immune and metabolic adaptations in a 34-year case of insidious progression [PDF]

Frontiers in Cardiovascular Medicine
BackgroundPulmonary arterial hypertension (PAH) is traditionally characterized as a rapidly progressive, fatal disease. Yet increasing evidence suggests that immune dysregulation, endothelial injury, and metabolic adaptation can sustain subclinical ...
Bronwen Erickson-Keith
doaj   +2 more sources

From multiple spleens to absence: Insights from two cases of heterotaxy syndromes [PDF]

Radiology Case Reports
Heterotaxy syndrome is a rare congenital disorder characterized by abnormal arrangement of the thoracic and abdominal organs and is classified into polysplenia (left isomerism) and asplenia (right isomerism) syndromes.
Suman Paudel, MD, Rishi Ram Banjade, MBBS, Niraj Kumar Sharma, MD, Sharmila Ghimire, MD, Prerana Singh Rokaha, MBBS   +4 more
doaj   +2 more sources

Long‐Term Outcomes and Risk Factors for Mortality After Single Ventricle Palliation for Asplenia Syndrome [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background This study evaluated the long‐term outcomes of asplenia syndrome with single ventricle palliation, hypothesizing that total anomalous pulmonary vein connection (TAPVC), pulmonary atresia (PA), and greater than or equal to moderate ...
Yasuyuki Kobayashi, Shunji Sano, Yuhei Tokuda, Ayari Kimura, Steven J. Staffa, David Zurakowski, Shingo Kasahara, Yasuhiro Kotani   +7 more
doaj   +2 more sources

Assessing the Vulnerability of Splenectomized Patients to Severe COVID-19 Outcomes: A Systematic Review and Meta-Analysis [PDF]

Vaccines
Background: Splenectomized/asplenic individuals are at a heightened risk for severe infections due to compromised immune function. However, the impact of splenectomy/asplenia on COVID-19 outcomes remains underexplored.
Francesco Paolo Bianchi, Massimo Giotta, Andrea Martinelli, Maria Grazia Giurgola, Giulia Del Matto, Elita Mastrovito, Maria Tina Fedele, Giuseppe Manca, Salvatore Minniti, Maurizio De Nuccio, Vincenzo Gigantelli, Silvio Tafuri, Stefano Termite   +12 more
doaj   +2 more sources

Autosplenectomy in a Patient With Autoimmune Polyglandular Syndrome Type 2 (APS-2) [PDF]

Case Reports in Endocrinology
Autoimmune glandular syndrome type 2 is a complex genetic condition where a triad of endocrinopathies is involved, namely, Addison’s disease, type 1 diabetes, and/or autoimmune thyroid disorder.
Luqman S. Fauzi, Airin Jyoty, Yashwin Sredharan, Manohara Kenchaiah   +3 more
doaj   +2 more sources

Asplenia in left isomerism

Annals of Pediatric Cardiology
Anatomical configurations where the viscero-atrial structures do not follow the usual arrangement or mirror-imaged arrangement is described conventionally as heterotaxy.
Usnish Adhikari, Venkatesh Gurajala, Palanisamy Dinesh Raja, Anoop Ayyappan, Deepti Narasimhaiah, Arun Gopalakrishnan   +5 more
doaj   +3 more sources

Asplenia and Fever [PDF]

Baylor University Medical Center Proceedings, 2015
A 45-year-old-man presented with the abrupt onset of a fever over 30 years after surgical splenectomy. He presented with symptoms and findings that seemed consistent with influenza. He rapidly developed fulminant meningitis that resulted in his death.
Mitchell L, Huebner, Kristin A, Milota
openaire   +2 more sources

Histoplasmosis and asplenia [PDF]

Thorax, 2010
A 42-year-old asplenic woman was evaluated for a 2-week history of intermittent high-grade fevers and pleuritic chest pain and skin rash (figure 1). A CT scan of the chest showed multiple small nodules on both lungs (figure 2). Fungal serological studies were negative. A skin biopsy revealed palisading dermal granulomatous …
Harris V K, Naina, Charles F, Thomas, Samar, Harris   +2 more
openaire   +2 more sources

Asplenia Syndrome in a Neonate: A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2016
Asplenia syndrome is a syndrome of right isomerism or attempted bilateral right sidedness. It includes congenital asplenia in association with complex congenital cyanotic heart disease and situs anomalies of the other thoracoabdominal organs.
Kapil Bhalla, Jasbir Singh, Jaivinder Yadav, Suchi Mehra   +3 more
doaj   +1 more source