Risk of invasive pneumococcal disease in patients with asplenia/hyposplenism: A nationwide population-based study in Korea, 2009–2018 [PDF]
International Journal of Infectious Diseases, 2020 Objectives: We aimed to determine the incidence and relative risk (RR) of invasive pneumococcal disease (IPD) in patients with asplenia/hyposplenism, using a nationwide population-based database.
Ji-Man Kang +5 more
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Human Vaccines & Immunotherapeutics, 2021 Patients with asplenia are at high risks of severe infections caused by encapsulated bacteria, particularly Streptococcus pneumoniae. Thirteen-valent pneumococcal conjugate vaccine (PCV13) and 23-valent pneumococcal polysaccharide vaccine (PPSV23) are ...
Kenichi Takeshita +7 more
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Case Report: Rethinking pulmonary arterial hypertension: immune and metabolic adaptations in a 34-year case of insidious progression [PDF]
Frontiers in Cardiovascular MedicineBackgroundPulmonary arterial hypertension (PAH) is traditionally characterized as a rapidly progressive, fatal disease. Yet increasing evidence suggests that immune dysregulation, endothelial injury, and metabolic adaptation can sustain subclinical ...
Bronwen Erickson-Keith
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Recurrent pulmonary vein stenosis potentially aggravated by posterior compression in a patient with asplenia [PDF]
Journal of Cardiothoracic SurgeryPulmonary vein stenosis after repair of total anomalous pulmonary venous connection (TAPVC) is a life-threatening complication that frequently recurs, particularly in patients with asplenia.
Takako Nishino, Makoto Ando
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Long‐Term Outcomes and Risk Factors for Mortality After Single Ventricle Palliation for Asplenia Syndrome [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground This study evaluated the long‐term outcomes of asplenia syndrome with single ventricle palliation, hypothesizing that total anomalous pulmonary vein connection (TAPVC), pulmonary atresia (PA), and greater than or equal to moderate ...
Yasuyuki Kobayashi +7 more
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From multiple spleens to absence: Insights from two cases of heterotaxy syndromes [PDF]
Radiology Case ReportsHeterotaxy syndrome is a rare congenital disorder characterized by abnormal arrangement of the thoracic and abdominal organs and is classified into polysplenia (left isomerism) and asplenia (right isomerism) syndromes.
Suman Paudel, MD +4 more
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Case Report: The effect of asplenia on the response to influenza vaccination and passive transfer of immunity in an adult female pig [PDF]
Frontiers in ImmunologyAsplenia is an important cause of morbidity and mortality in humans. However, there are only very rare examples of this condition reported in domesticated species. Here we present a case of asplenia, diagnosed at necropsy, in a crossbred adult female pig
Michael C. Rahe +5 more
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Autosplenectomy in a Patient With Autoimmune Polyglandular Syndrome Type 2 (APS-2) [PDF]
Case Reports in EndocrinologyAutoimmune glandular syndrome type 2 is a complex genetic condition where a triad of endocrinopathies is involved, namely, Addison’s disease, type 1 diabetes, and/or autoimmune thyroid disorder.
Luqman S. Fauzi +3 more
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Asplenia Syndrome in a Neonate: A Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2016 Asplenia syndrome is a syndrome of right isomerism or attempted bilateral right sidedness. It includes congenital asplenia in association with complex congenital cyanotic heart disease and situs anomalies of the other thoracoabdominal organs.
Kapil Bhalla +3 more
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Frontiers in Physiology, 2022 Sickle cell disease (SCD) is caused by a point mutation in the beta-globin gene. SCD is characterized by chronic hemolytic anemia, vaso-occlusive events leading to tissue ischemia, and progressive organ failure.
Sari Peretz +11 more
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