Results 161 to 170 of about 9,760 (198)

Asplenia and spleen hypofunction

Nature Reviews Disease Primers, 2022
Asplenia (the congenital or acquired absence of the spleen) and hyposplenism (defective spleen function) are common causes of morbidity and mortality. The spleen is a secondary lymphoid organ that is responsible for the regulation of immune responses and blood filtration.
Marco Vincenzo Lenti, Sarah Luu, Rita Carsetti, Faith Osier, Rodney Ogwang, Obiageli E. Nnodu, Ursula Wiedermann, Jo Spencer, Franco Locatelli, Gino Roberto Corazza, Antonio Di Sabatino   +10 more
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Asplenia congenita

Medico e Bambino pagine elettroniche, 2020
The paper presents a case of congenital asplenia diagnosed occasionally in a child who previously presented with a pneumococcal sepsis. The case offers the opportunity to discuss about the elevated risk of severe invasive infections in patients with congenital asplenia and the importance of early diagnosis so to prevent infections by starting an ...
Migliarino, Vanessa, Lapenna, Roberta, Comici, Alberto, Miani, Maria Paola, Naviglio, Samuele, Barbi, Egidio   +5 more
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Sepsis and congenital asplenia

The Journal of Pediatrics, 1977
Fifty-nine children with congenital asplenia were reviewed for episodes of severe infection. Seven children had isolated asplenia and 52 had asplenia associated with complex congenital heart disease (asplenia syndrome). A control group of eusplenic children with comparable cardiac lesions were assembled and used for comparative statistical analysis ...
J D, Waldman, A, Rosenthal, A L, Smith, S, Shurin, A S, Nadas   +4 more
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Congenital asplenia study: clinical and laboratory characterisation of adults with congenital asplenia

Annals of Hematology, 2022
Congenital asplenia is a rare disorder commonly associated with other visceral and cardiac congenital anomalies. Isolated congenital asplenia is even less common than syndromic forms. The risk of severe bacterial infections associated with asplenia is the most concerning clinical implication and carries a significant mortality risk.
Grace I, Butel-Simoes, Penelope, Jones, Erica M, Wood, Denis, Spelman, Ian J, Woolley, Samar, Ojaimi   +5 more
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ASPLENIA AND POLYSPLENIA SYNDROME

Acta Pathologica Japonica, 1982
This report described the morphological characteristics of seven cases of asplenia syndrome and three of polysplenia syndrome. Each syndrome has been characterized by a tendency for symmetric development of normally asymmetric organs, with varying degrees of cardiovascular anomalies.
Y, Shinohara, S, Komiya, A, Nakashima, T, Nakashima, S, Takeuchi, E, Ono, S, Yukizane, C, Tanaka, T, Matsuishi, T, Koga, Y, Hieda, H, Nakashima, A, Ichikawa   +12 more
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Thrombotic Angiitis and Congenital Asplenia

JAMA: The Journal of the American Medical Association, 1965
THE SPLEEN has a well-known role in the regulation of blood thrombocyte levels, and its absence may contribute to the occurrence of recurrent infections, as cited by Smith et al 1 and Finland. 2 We have recently cared for a middle-aged man with congenital absence of the spleen, who had pneumonia, an acute inflammatory aortic-arch syndrome, and multiple
G J, GILBERT, P J, PHILLIPPI, L J, SCRIPTER   +2 more
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Asplenia and Polysplenia

Journal of Diagnostic Medical Sonography, 1991
Abdominal sonograms on seven patients with asplenia syndrome and six patients with polysplenia syndrome were retrospectively reviewed. All seven patients with asplenia had a horizontal symmetric configuration of the liver, and three patients had the cardiac apex opposite the stomach.
Raksha K. Patel, Glenn A. Rouse, Phil-Ann Tan-Sinn   +2 more
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The Concept of Functional Asplenia

New England Journal of Medicine, 1969
Removal of the normal spleen (for example, after trauma or during abdominal operations on adjacent structures) is often followed by the appearance of abnormal red cells in the peripheral blood. In certain hematologic disorders in which the spleen is enlarged and is believed to be hyperactive, splenectomy can result in a strikingly bizarre blood smear ...
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