Results 161 to 170 of about 3,875,152 (312)

Evaluation of harmonization methods to mitigate assay and cohort effects in plasma p-tau217. [PDF]

Alzheimers Dement (Amst)
Zhang VZ, Ferreira PCL, Dong Y, Minhas D, Povala G, Bellaver B, Alzheimer's Disease Neuroimaging Initiative, Pascoal TA, Zeng X, Karikari TK, Cohen AD, Deek RA, Wu Q, Tudorascu DL.   +13 more
europepmc   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

An endpoint multiplex PCR/RT-PCR for detection of viral agents of bovine respiratory disease. [PDF]

Braz J Microbiol
Alessio NHP, Silva Júnior JVJ, Dionisio IF, Dos Santos VS, Gomes V, Weiblen R, Flores EF.   +6 more
europepmc   +1 more source

Noninvasive multianalyte diagnostic assay for monitoring bladder cancer recurrence

, 2012
Neal D Shore,1 Cecilia A Fernandez,2 Anthony P Shuber21Carolina Urologic Research Center/Atlantic Urology Clinics, Myrtle Beach, SC, 2Predictive Biosciences Inc, Lexington, MA, USABackground: The purpose of this study was to establish the clinical ...
Shore ND, Shuber AP, Fernandez CA
core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Development of a One-Step RT-LAMP-CRISPR/Cas12b Assay for Rapid On-Site Detection of Dabie Bandavirus. [PDF]

ACS Omega
Guo J, Wu T, Qiao Q, Zhu X, Zhao K, Cui L, Huo X, Ge Y.   +7 more
europepmc   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Quantification of Antibody-Drug Conjugate Targets in Head and Neck Squamous Cell Carcinoma. [PDF]

Mol Cancer Ther
He M, Trontzas IP, Bates KM, Burela S, Moutafi M, Ahmed FS, Shafi S, Robbins CJ, Liebler DC, Fulton R, Burtness BA, Rimm DL.   +11 more
europepmc   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

Development of shelf-stable reagents and assay kits for bioluminescence applications using the capillary-assisted vitrification platform stabilization technology. [PDF]

PLoS One
Radford S, Peris-Taverner Y, Dibble M, Corn K, Zhu T, Martello S, Mayeaux M, Ladd A, Renu S, Chunduri T, Jadhav A, Dart M, Rafat M, Shank-Retzlaff M, Bronsart LL.   +14 more
europepmc   +1 more source