Peptide-Linked Bivalent Nanobody Constructs as Positive Allosteric Modulators of the Calcium-Sensing Receptor. [PDF]
Basic Clin Pharmacol ToxicolNabipour M +5 more
europepmc +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Differentiating Avian and Seasonal Influenza Viruses in Wastewater by Digital PCR. [PDF]
Emerg Infect DisParacchini V +15 more
europepmc +1 more source
Fischer Assay Data, Utah Geological Survey Well Number U081
, 2008 datasethis dataset contains the results of Fischer assay analyses obtained and published by the Utah Geological Survey for well ...
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Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Assessing the Age-Specific Seroepidemiology of Varicella-Zoster Virus in Korea in the Post-COVID-19 Era Using an Acetone-Fixed Cell FAMA Assay. [PDF]
J Korean Med SciKang KR +24 more
europepmc +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Compressible but not redundant: knockout recovery and assay-panel architecture of the Neurospora crassa deletion phenome. [PDF]
G3 (Bethesda)Ahn E +5 more
europepmc +1 more source
, 2011 The aim of this study was to evaluate the diagnostic performance of an enzyme-linked immunospot (ELISPOT) assay for interferon-gamma in patients with suspected genitourinary tuberculosis (TB). A total of 30 patients with suspected genitourinary TB at the
LAI, CHIH-CHENG;TAN, CHE-KIM;LIN, SHENG-HSIANG;LIAO, CHUN-HSIN;HUANG, YU-TSUNG;WANG, CHENG-YI;WANG, JEN-YU;LIN, HEN-I;HSUEH, PO-REN +1 more
core
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source