Results 51 to 60 of about 182,023 (289)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
, 2021 Understanding the species assemblage and foraging behavior of demersal fishes and large invertebrates occurring at False Bay was the primary objective of this study.
Nguyen, Adam
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Tokyo Metropolitan Parks as urban forestry assemblagesreframing more-than-human commons in the city
Journal of Asian Architecture and Building Engineering, 2022 This study explores urban forestry as a maintenance practice capable of enhancing more-than-human commons in the city. Focusing on the places associated with tree care, the methodology takes as a case study the Tokyo Metropolitan Parks, conducting ...
Diego Martín Sánchez +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
, 2022 Hyperreal architectural assemblages are pervading our daily experience and progressively disrupting our spatial practices. Thought-provoking paradigms using VAM (virtual, augmented and mixed) realities profoundly transform our perception of space ...
Manfredini, Manfredo, Pretty, Annabel
core
Translocation in a fragmented river provides demographic benefits for imperiled fishes
EcosphereFragmentation isolates individuals and restricts access to valuable habitat with severe consequences for populations, such as reduced gene flow, disruption of recolonization dynamics, reduced resiliency to disturbance, and changes in aquatic community ...
Casey A. Pennock +6 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Fixing Non-market Subjects: Governing Land and Population in the Global South
Foucault Studies, 2014 Expert knowledge about society and human nature is essential to governing human conduct. It figures in the formulation of the liberal and neoliberal rationalities of government that Foucault analyzed in his later work.
Tania Murray Li
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source