Results 31 to 40 of about 1,175,139 (268)

N-Dopant-Mediated Growth of Metal Oxide Nanoparticles on Carbon Nanotubes

open access: yesNanomaterials, 2021
Metal oxide nanoparticles supported on heteroatom-doped graphitic surfaces have been pursued for several decades for a wide spectrum of applications. Despite extensive research on functional metal oxide nanoparticle/doped carbon nanomaterial hybrids, the
Jin Ah Lee   +3 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Dynamic Obstacle Avoidance for Unmanned Underwater Vehicles Based on an Improved Velocity Obstacle Method

open access: yesSensors, 2017
In view of a dynamic obstacle environment with motion uncertainty, we present a dynamic collision avoidance method based on the collision risk assessment and improved velocity obstacle method.
Wei Zhang   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Multi-objective topology optimization and structural analysis of periodic spaceframe structures

open access: yesMaterials & Design, 2020
Reduction of structural weight provides significant benefits in many engineering applications. While methods to optimise structural shape and topology of both continuous solids and discrete frame structures have existed for a while, the advent of ...
Jarad Lim, Chao You, Iman Dayyani
doaj   +1 more source

The Phusion Assembler [PDF]

open access: yesGenome Research, 2002
The Phusion assembler has assembled the mouse genome from the whole-genome shotgun (WGS) dataset collected by the Mouse Genome Sequencing Consortium, at ∼7.5× sequence coverage, producing a high-quality draft assembly 2.6 gigabases in size, of which 90% of these bases are in 479 scaffolds.
James C, Mullikin, Zemin, Ning
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Spatio-temporal relays control layer identity of direction-selective neuron subtypes in Drosophila

open access: yesNature Communications, 2018
Direction-selective T4/T5 neurons show layer-specific projections in the fly visual circuit. Examining the mechanisms behind their development, the authors found that a relay of Wnt and Bmp signaling across neuroepithelial domains and transcription ...
Holger Apitz, Iris Salecker
doaj   +1 more source

Investigation of Parameters of Fused Deposition Modelling 3D Prints with Compression Properties

open access: yesAdvances in Materials Science and Engineering, 2022
Three-dimensional (3D) printing has been attracting a great deal of attention in recent years in many application fields, for example, in the aerospace, construction, industry, art, education, protection, security, and medical fields.
Dereje Berihun Sitotaw   +3 more
doaj   +1 more source

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