Results 41 to 50 of about 2,004,232 (316)

Multi-objective topology optimization and structural analysis of periodic spaceframe structures

open access: yesMaterials & Design, 2020
Reduction of structural weight provides significant benefits in many engineering applications. While methods to optimise structural shape and topology of both continuous solids and discrete frame structures have existed for a while, the advent of ...
Jarad Lim, Chao You, Iman Dayyani
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Melanotic oncocytic metaplasia of the nasopharynx: A case report discussing the pathogenesis of a lesion

open access: yesOtolaryngology Case Reports, 2021
Background: Melanotic oncocytic metaplasia is a rare non-neoplastic lesion. It has been described as a phenomenon in which cells change their morphology to adapt to various stimuli. The incidence of melanotic oncocytic metaplasia is higher in middle-aged
Shina Sakaguchi   +6 more
doaj   +1 more source

The Phusion Assembler [PDF]

open access: yesGenome Research, 2002
The Phusion assembler has assembled the mouse genome from the whole-genome shotgun (WGS) dataset collected by the Mouse Genome Sequencing Consortium, at ∼7.5× sequence coverage, producing a high-quality draft assembly 2.6 gigabases in size, of which 90% of these bases are in 479 scaffolds.
James C, Mullikin, Zemin, Ning
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Spatio-temporal relays control layer identity of direction-selective neuron subtypes in Drosophila

open access: yesNature Communications, 2018
Direction-selective T4/T5 neurons show layer-specific projections in the fly visual circuit. Examining the mechanisms behind their development, the authors found that a relay of Wnt and Bmp signaling across neuroepithelial domains and transcription ...
Holger Apitz, Iris Salecker
doaj   +1 more source

Investigation of Parameters of Fused Deposition Modelling 3D Prints with Compression Properties

open access: yesAdvances in Materials Science and Engineering, 2022
Three-dimensional (3D) printing has been attracting a great deal of attention in recent years in many application fields, for example, in the aerospace, construction, industry, art, education, protection, security, and medical fields.
Dereje Berihun Sitotaw   +3 more
doaj   +1 more source

N-Dopant-Mediated Growth of Metal Oxide Nanoparticles on Carbon Nanotubes

open access: yesNanomaterials, 2021
Metal oxide nanoparticles supported on heteroatom-doped graphitic surfaces have been pursued for several decades for a wide spectrum of applications. Despite extensive research on functional metal oxide nanoparticle/doped carbon nanomaterial hybrids, the
Jin Ah Lee   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Concept and implementation of an agent-based control architecture for a cyber-physical assembly system

open access: yesMATEC Web of Conferences, 2016
Today’s production companies are challenged with: the assembly of different product variants with lot size of one on a single assembly line and the increase of product variants.
Müller Rainer   +4 more
doaj   +1 more source

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