Results 41 to 50 of about 1,175,139 (268)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Reinventing local food supply in connected cities: The example of The Food Assembly
Field Actions Science Reports, 2017 The Food Assembly (La Ruche Qui Dit Oui ! in French) is a social and collaborative enterprise created following a two-fold observation: crop and livestock farmers face financial difficulties while end-consumers aspire to new modes of consumption.
The Food Assembly team
doaj
Polar Grid Navigation Algorithm for Unmanned Underwater Vehicles
Sensors, 2017 To solve the unavailability of a traditional strapdown inertial navigation system (SINS) for unmanned underwater vehicles (UUVs) in the polar region, a polar grid navigation algorithm for UUVs is proposed in this paper.
Zheping Yan +4 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Journal of Ophthalmic Inflammation and InfectionBackground Vogt-Koyanagi-Harada (VKH) disease affects visual function, but the recovery process of color vision remains incompletely understood.
Tomoko Nakamura +4 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The Resolution of the World Health Assembly on the Elimination of Avoidable Blindness
Community Eye Health Journal, 2003 WHA 56.26. Agenda Item 14.17: 28 May 2003.
Fifty-sixth World Health Assembly
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Localized Amyloidosis of the Nasal Mucosa: A Case Report and Review of the Literature
Frontiers in Surgery, 2021 Amyloidosis is a disorder of protein folding in which various proteins automatically aggregate into a highly abnormal fibrillar conformation. Amyloidosis is classified into systemic and localized forms depending on whether the abnormal proteins deposited
Hiromasa Takakura +4 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
MATEC Web of Conferences, 2016 Today’s production companies are challenged with: the assembly of different product variants with lot size of one on a single assembly line and the increase of product variants.
Müller Rainer +4 more
doaj +1 more source