Results 61 to 70 of about 2,010,216 (316)

Developmental divergence of sensory stimulus representation in cortical interneurons

open access: yesNature Communications, 2020
Sensory neuronal circuits adapt during maturation when animals start to actively interact with the external world. The authors reveal structural and functional rearrangements of the input cortical interneurons receive around the time the animals start ...
Rahel Kastli   +9 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Assembly of the Union Seventeenth Ordinary Session 30 June - 1 July 2011 Malabo, Equatorial Guinea [PDF]

open access: yes, 2011
Decision on the Theme “Accelerating Youth Empowerment for Sustainable Development” – Doc.
The Assembly
core  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Decision on the “Convening of Mid-Year Sessions of the Assembly of the African Union (July Sessions)” Doc. Assembly/Au/17(Xv)Add.11 [PDF]

open access: yes, 2005
Decision Assembly/AU/Dec.63(IV) on the Framework for The Organization of Future Summits adopted at its Fourth Ordinary Session held in Abuja, Nigeria, in January ...
The Assembly
core  

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Decision on the Offer of the Republic of Chad to Host the Assembly of the African Union in June/July 2015 Doc. Assembly/Au/14(Xviii) Add.1 [PDF]

open access: yes, 2015
Government of the Republic of Chad to host the Twenty-Fifth Ordinary Session of the Assembly of the African Union in June/July ...
The Assembly
core  

Evaluating staging laparoscopy indications for pancreatic cancer based on resectability classification and treatment strategies for patients with positive peritoneal washing cytology

open access: yesAnnals of Gastroenterological Surgery
Introduction The prognosis of pancreatic ductal adenocarcinoma (PDAC) in patients with positive peritoneal washing cytology (CY1) is poor. We aimed to evaluate the results of staging laparoscopy (SL) and treatment efficacy in CY1 patients based on a ...
Takamichi Igarashi   +9 more
doaj   +1 more source

Assembling the pieces [PDF]

open access: yesNature Chemical Biology, 2008
Transition metals function as cofactors in specific proteins, catalyzing electron exchange reactions, binding substrates and stabilizing protein structure. Studies of human diseases and of model organisms have defined many of the molecular details of metal uptake, trafficking, and excretion.
Dennis J, Thiele, Jonathan D, Gitlin
openaire   +2 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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