Results 111 to 120 of about 6,607,658 (283)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Research on Dynamic Dispatching Rule for Semiconductor Assembly Production Line

, 2012
We propose a dynamic dispatching rule for semiconductor assembly production line based on the current mainstream dynamic dispatching rules. In particular, our dispatching rule considers batch dispatching.
Zhu Jun, Zhu J(朱军), Rong Yuan, Chen Hai-Zan, Chen HZ(陈海赞), Liu Chang, Liu C(刘昶), Yuan, Rong   +7 more
core   +1 more source

A case study on implementation of walking worker assembly line to improve productivity and utilisation of resources in a heavy duty manufacturing industry [PDF]

FME Transactions, 2017
The current industry demands high productivity removing every constraint inherited during manufacturing a product with limited resources. Reconfigurability and Flexibility to produce multiple components depending on customer demand is a key factor.
Deepak A., Srivatsan R., Samsingh V.
doaj  

Performance Comparison Of Two Assembly Line Concepts: Conveyor Line And Box Assembly Line

, 2012
{"references": ["G. Chryssolouris, N. Papakostas, \"A perspective on manufacturing\nstrategy: produce more with less,\" CIRP Journal Manufacturing Science\nand Technology, vol. 1 iss. 1, pp. 42-52, Jan. 2008", "M. Sako, M. Warburton, \"Modularization and outsourcing project,\npreliminary report of European research team,\" prepared for the IMVP\nAnnual
Kezia Amanda Kurniadi, Emre Islamoglu, Kwangyeol Ryu   +2 more
openaire   +2 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

The ribosomal subunit assembly line.

Genome biology, 2005
Recent proteomic studies in Saccharomyces cerevisiae have identified nearly 200 proteins, other than the structural ribosomal proteins, that participate in the assembly of ribosomal subunits and their transport from the nucleus. In a separate line of research, proteomic studies of mature plant ribosomes have revealed considerable variability in the ...
openaire   +2 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Automated Assembly Line with 2D Cartesian Robot and Conveyor Belt

International Journal of Technology
Industrial automation is constantly developing and considered critical to process optimization and efficiency. The integration of automated systems is traditionally focused on improving precision and productivity to significantly enhance assembly lines ...
Viviana Moya, María Maldonado, Juan Pablo Vásconez, Faruk Abedrabbo, David Pozo-Espin, Marcelo Moya   +5 more
doaj   +1 more source