Results 121 to 130 of about 6,607,658 (283)

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

From Apprenticeship to Assembly Line: Recovering Relationships in Medical Education. [PDF]

J Grad Med Educ, 2023
Sawatsky AP, Rea JR, Hafdahl LT, Vaa Stelling BE, Huber JM, Wingo MT, Leasure EL.   +6 more
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Genomic mining and diversity of assembly line polyketide synthases. [PDF]

Open Biol, 2023
Kishore S, Khosla C.
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

FASTory assembly line power consumption data. [PDF]

Data Brief, 2023
Elahi M, Afolaranmi SO, Mohammed WM, Martinez Lastra JL.   +3 more
europepmc   +1 more source

Ultrafast visual detection of Streptococcus suis via HtpsC‐targeted LAMP–CRISPR–Cas12a coupled with lateral flow immunochromatography

FEBS Open Bio, EarlyView.
A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li, Miao Xin, Xiao‐wen Cui, Shi‐yin Yu, Fei Meng, Min Cao, Xiao‐hui Xiong, Yi‐chen Lu   +7 more
wiley   +1 more source

Research on optimization method for hybrid assembly line design

, 2004
In a dynamical manufacturing environment hybrid assembly line is used widely because of its flexibility and reconfigurability. Hybrid assembly line design problem is more difficult and complex than ordinary simple line design problems.
Qin YF(秦永法), Zhao MY(赵明扬)
core  

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Workplace Safety in Industry 4.0 and Beyond: A Case Study on Risk Reduction Through Smart Manufacturing Systems in the Automotive Sector

Safety
An important step toward automation and digitization in Industry 4.0 is the automobile sector’s use of smart manufacturing integrated systems (SMISs).
Alin Nioata, Alin Țăpirdea, Oana Roxana Chivu, Anamaria Feier, Ioana Catalina Enache, Marilena Gheorghe, Claudia Borda   +6 more
doaj   +1 more source