Results 31 to 40 of about 3,076,828 (236)

The Golgi as an Assembly Line to the Autophagosome [PDF]

Trends in Biochemical Sciences, 2020
Autophagy is traditionally depicted as a signaling cascade that culminates in the formation of an autophagosome that degrades cellular cargo. However, recent studies have identified myriad pathways and cellular organelles underlying the autophagy process, be it as signaling platforms or through the contribution of proteins and lipids. The Golgi complex
De Tito, Stefano, Hervas, Javier H., van Vliet, Alexander R., Tooze, Sharon A.   +3 more
openaire   +4 more sources

Heuristic Control of the Assembly Line

, 2015
The paper highlights the mathematical model of the assembly process for the automated line as well as sequence control algorithms for the assembled version of objects. The automatic assembly line control requires numerical simulation. Minimizing the assembly time of all objects or maximizing the number of assembled objects within the given time are ...
Bronislav Chramcov, Franciszek Marecki, Robert Bucki   +2 more
openaire   +2 more sources

A survey of the parallel assembly lines balancing problem [PDF]

, 2020
Assembly lines are mass production systems which are significant in the industrial production of both standard and customised products. Currently, industrial companies offer several products and it is common for an assembly system to have multiple ...
García Villoria, Alberto, Aguilar Gamarra, Harry Nick, Pastor Moreno, Rafael   +2 more
core   +1 more source

A review on assembly sequence planning and assembly line balancing optimisation using soft computing approaches [PDF]

, 2011
Assembly optimisation activities occur across development and production stages of manufacturing goods. Assembly Sequence Planning (ASP) and Assembly Line Balancing (ALB) problems are among the assembly optimisation.
Tiwari, Ashutosh, Mohd Fadzil Faisae Rashid, Windo Hutabarat, Ashutosh Tiwari, Hutabarat, Windo, Ab Rashid, Mohd Fadzil Faisae, Villanueva-Portela, Miguel Angel, Ramírez-Heredia, Ricardo Emiro   +7 more
core   +1 more source

Fast Task Scheduling With Model Predictive Control Integrating a Priority-Based Heuristic

IEEE Access
This paper presents a scalable Model Predictive Control (MPC) algorithm for task scheduling and real time re-scheduling. The use case motivating the work is given by the problem of managing the integration activities involved in the final assembly of the
Francesco Liberati, Manuel Donsante, Chiara Maria Francesca Cirino, Andrea Tortorelli   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Multiobjective Fuzzy Mixed Assembly Line Sequencing Optimization Model

Journal of Applied Mathematics, 2014
It can be deduced from previous studies that there exists a research gap in assembly line sequencing optimization model for mixed-model production lines.
Farzad Tahriri, Siti Zawiah Md Dawal, Zahari Taha   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The Bernoulli Assembly Line: The Analytical and Semi-Analytical Evaluation of Steady-State Performance

Applied Sciences, 2022
Assembly lines are one of the cornerstones of modern production systems, significantly affecting the global society, economy, and other ancillary sectors. This is why the evaluation of assembly lines is particularly significant.
Neven Hadžić, Viktor Ložar, Tihomir Opetuk, Zoran Kunkera   +3 more
doaj   +1 more source