Results 41 to 50 of about 3,076,828 (236)

A global assembly line for cyanobactins [PDF]

open access: yesNature Chemical Biology, 2008
More than 100 cyclic peptides harboring heterocyclized residues are known from marine ascidians, sponges and different genera of cyanobacteria. Here, we report an assembly line responsible for the biosynthesis of these diverse peptides, now called cyanobactins, both in symbiotic and free-living cyanobacteria.
Mohamed S, Donia   +2 more
openaire   +2 more sources

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Learning curve-based scheduling in customized assembly lines

open access: yesRevista Produção Online, 2011
Mass customization implies in large variety of product models and small lot sizes. Human-based activities are highly affected by the learning process as a new model is put into production.
Michel J. Anzanello, Flavio S. Fogliatto
doaj   +1 more source

Balancing Workload and Workforce Capacity in Lean Management: Application to Multi-Model Assembly Lines

open access: yesApplied Sciences, 2020
While multi-model assembly lines are used by advanced lean companies because of their flexibility (different models of a product are produced in small lots and reach the customers in a short lead time), most of the extant literature on how to staff ...
Jordi Fortuny-Santos   +3 more
doaj   +1 more source

Solving stochastic multi-manned U-shaped assembly line balancing problem using differential evolution algorithm

open access: yesInternational Journal of Production Management and Engineering, 2022
The U-shaped assembly lines help to have more flexibility than the straight assembly lines, where the operators can perform tasks in both sides of the line, the entrance and the exit sides.
Mohammad Zakaraia   +2 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Enhancing throughput in labor intensive assembly lines [PDF]

open access: yesE3S Web of Conferences
This study aims to optimize Company X’s labor-intensive production line to significantly improve operational efficiency and reduce long-standing bottlenecks. Company X is located in Perak State, Malaysia.
Ang Zixuan   +2 more
doaj   +1 more source

Modeling of the two shuttle box system within the internal logistics system using simulation software

open access: yesOpen Engineering, 2021
The efficiency and effectiveness of the production system are influenced by the logistical arrangement of material flows. The smooth production, especially for assembly lines in the required quantity and at the required time (JIT or JIS systems), is ...
Strnad David   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

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