Results 151 to 160 of about 5,534,789 (298)
Response to letter to the editor: Awareness strategies and the physiological impact of pain in prehospital analgesia management. [PDF]
Wennberg P, Larsson G, Wibring K.
europepmc +1 more source
Penicillin V--Clinical Assessment After One Year [PDF]
R. Lamb, E. S. Maclean
openalex +1 more source
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair+17 more
wiley +1 more source
Human health risk assessment for microbial pesticides in the EU: challenges and perspectives. [PDF]
Barrero-Canosa J+6 more
europepmc +1 more source
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes+20 more
wiley +1 more source
Inventory of self-assessed competences: a tool for identifying training strengths and weaknesses in medical and multiprofessional residency programmes for primary health care. [PDF]
de Fátima Diniz Souza É+10 more
europepmc +1 more source
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser+11 more
wiley +1 more source
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source