Results 221 to 230 of about 14,098,287 (316)

Implementation and Evaluation of a Pediatric Pain Assessment Educational Program (PPAEP) for Nurses in a Resource-Limited Setting: A Pilot Study. [PDF]

Paediatr Neonatal Pain
Kusi Amponsah A, Hammond CK, Bam V, Gyamfi D, Armah J, Wilson D, Annobil F, Badengo DB, Danquah CB, Dompim JK, Axelin A, Nawagi F, Mukherjee S.   +12 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Reproductive health - a blind spot in psychotherapeutic treatment? Evidence of insufficient consideration of reproductive factors in routine care. [PDF]

Dialogues Clin Neurosci
Engel S, Langer JS, Maaß E, Richter J.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

The Epidemiological Profile of Older Adults of Pacific Peoples Ethnicity in New Zealand Assessed for Home Support and Aged Residential Care. [PDF]

Australas J Ageing
Walker X, Abey-Nesbit R, Kayes J, Bergler HU, Cheung G, Waters D, Grey C, Stuart M, Jamieson H.   +8 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Video-Based Skill Assessment for Postoperative T-Tube Nursing is Associated with Improved Clinical Outcomes and Patient Satisfaction: A Single-Center Retrospective Comparative Study. [PDF]

J Multidiscip Healthc
Zhang B, Li Y, Zhao H.
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Ultrasound Assessment of the Anterolateral Ligament of the Knee: A Narrative Review of Current Evidence, Interpretative Limitations, and Clinical Context. [PDF]

Diagnostics (Basel)
Niewiadomy P, Szuścik-Niewiadomy K.
europepmc   +1 more source