Results 111 to 120 of about 333,852 (304)

Medication adherence to inhalation therapy and the risk of COPD exacerbations: a systematic review with meta-analysis

BMJ Open Respiratory Research
Background Assessing medication adherence is crucial in chronic obstructive pulmonary disease (COPD) management to prevent exacerbations. However, it is unclear whether this association between adherence and exacerbations is influenced by the adherence ...
Lies Lahousse, Maxim Grymonprez, Anna Vanoverschelde, Delphine Vauterin, Frauke Van Vaerenbergh   +4 more
doaj   +1 more source

Self-Efficacy as Moderator and Mediator Between Medication Beliefs and Adherence in Elderly Patients with Type 2 Diabetes

Patient Preference and Adherence, 2023
Jianbo Wu, Jie Shen, Zhujun Tao, Zhongjuan Song, Zhi-Long Chen Department of Pharmacy, Huadong Hospital, Fudan University, Shanghai, People’s Republic of ChinaCorrespondence: Jie Shen; Zhi-Long Chen, Email shj421@126.com; zlchen1967@qq.comPurpose: Poor ...
Wu J, Shen J, Tao Z, Song Z, Chen ZL
doaj  

Adherence in Rheumatoid Arthritis patients assessed with a validated Italian version of the 5-item compliance questionnaire for rheumatology [PDF]

, 2019
OBJECTIVES: The 5-item Compliance Questionnaire for Rheumatology (CQR5) proved reliability and validity in respect of identification of patients likely to be high adherers (HAs) to anti-rheumatic treatment, or low adherers (LAs), i.e ...
Astorri, D., Azzolina , D., Botsios, C., Done, John, Doria, A, Favero, M, Friso, L, Gregori, D, Ometto, Francesca, Raffeiner, B.   +9 more
core  

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

The clinical effectiveness and cost-effectiveness of inhaler devices used in the routine management of chronic asthma in older children: a systematic review and economic evaluation [PDF]

, 2002
Background: This review examines the clinical effectiveness and cost-effectiveness of hand-held inhalers to deliver medication for the routine management of chronic asthma in children aged between 5 and 15 years.
Beverley, C., Lim, J.N.W., Peters, J., Smith, S., Stevenson, M.   +4 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Editorial: Recent advances in attempts to improve medication adherence-from basic research to clinical practice

Frontiers in Pharmacology, 2023
Przemyslaw Kardas, Alexandra L. Dima, Alexandra L. Dima, Ines Potočnjak, Bjorn Wettermark, Bjorn Wettermark, Tamas Agh, Tamas Agh   +7 more
doaj   +1 more source

Medication adherence in first-episode psychosis and its association with psychopathology

Indian Journal of Psychiatry, 2019
Background: The purpose of the study was to follow-up the individuals with first-episode psychosis (FEP) for a period of 1 year to assess their medication adherence rates and to identify the association between medication adherence and psychopathology ...
Vijaya Raghavan, Greeshma Mohan, Subhashini Gopal, Mangala Ramamurthy, Thara Rangaswamy   +4 more
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source