Results 181 to 190 of about 1,602,944 (312)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Validation and Reproducibility of an App for Continuous Measurement as an Assessment Tool for Idiopathic Scoliosis. [PDF]

Sensors (Basel)
Navarro IJRL, Jacob L, Masetto K, Dulio F, Negrini A, Negrini S, Zaina F, Negrini A.   +7 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Developing the Community Paramedicine Needs Assessment Tool. [PDF]

Nurs Rep
Markides TM, Shannon B, Cameron C, Hussain A, Caperon L, Batt AM.   +5 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Validity and Reliability of the Burnout Assessment Tool (BAT) in Serbian. [PDF]

Healthcare (Basel)
Terzic-Supic Z, Stratakis K, Candido T, Nikolov Z, Galjak M, Nesic D, Aleksandric G, Radaljac D, Todorovic J.   +8 more
europepmc   +1 more source

Research progress on fear of falling in patients with hip fracture

Huli yanjiu, 2022
XU Yaqin, XIE Caixia
doaj  

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Proposed Risk of Bias Assessment Tool for <i>In Vitro</i> Antimicrobial Susceptibility Studies. [PDF]

Pathogens
Falagas ME, Ragias D, Kontogiannis DS, Romanos LT, Farazi PA.   +4 more
europepmc   +1 more source

Research progress on loneliness status and its influencing factors in patients with type 2 diabetes mellitus

Huli yanjiu, 2022
BI Yaxin, ZHANG Lu, LI Xiangning, KAN Yinshi, LIU Hongyuan, LI Shuang, ZHANG Yu   +6 more
doaj